Highly efficient Cas9-mediated transcriptional programming A Chavez, J Scheiman, S Vora, BW Pruitt, M Tuttle, E PR Iyer, S Lin, ... Nature methods 12 (4), 326-328, 2015 | 1689 | 2015 |
Genetic engineering of human pluripotent cells using TALE nucleases D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao, JP Cassady, GJ Cost, ... Nature biotechnology 29 (8), 731-734, 2011 | 1592 | 2011 |
An enhanced CRISPR repressor for targeted mammalian gene regulation NC Yeo, A Chavez, A Lance-Byrne, Y Chan, D Menn, D Milanova, ... Nature methods 15 (8), 611-616, 2018 | 485 | 2018 |
Cas9 gRNA engineering for genome editing, activation and repression S Kiani, A Chavez, M Tuttle, RN Hall, R Chari, D Ter-Ovanesyan, J Qian, ... Nature methods 12 (11), 1051-1054, 2015 | 371 | 2015 |
CRISPR transcriptional repression devices and layered circuits in mammalian cells S Kiani, J Beal, MR Ebrahimkhani, J Huh, RN Hall, Z Xie, Y Li, R Weiss Nature methods 11 (7), 723-726, 2014 | 243 | 2014 |
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes SR Ferdosi, R Ewaisha, F Moghadam, S Krishna, JG Park, ... Nature communications 10 (1), 1842, 2019 | 188 | 2019 |
Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6 P Guye, MR Ebrahimkhani, N Kipniss, JJ Velazquez, E Schoenfeld, ... Nature communications 7 (1), 10243, 2016 | 175 | 2016 |
The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ... Nature 592 (7853), 195-204, 2021 | 111 | 2021 |
Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells R Forster, K Chiba, L Schaeffer, SG Regalado, CS Lai, Q Gao, S Kiani, ... Stem cell reports 2 (6), 838-852, 2014 | 102 | 2014 |
Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats MR Ebrahimkhani, S Kiani, F Oakley, T Kendall, A Shariftabrizi, ... Gut 55 (11), 1606-1616, 2006 | 102 | 2006 |
Gene regulatory network analysis and engineering directs development and vascularization of multilineage human liver organoids JJ Velazquez, R LeGraw, F Moghadam, Y Tan, J Kilbourne, JC Maggiore, ... Cell systems 12 (1), 41-55. e11, 2021 | 82 | 2021 |
Accurate predictions of genetic circuit behavior from part characterization and modular composition N Davidsohn, J Beal, S Kiani, A Adler, F Yaman, Y Li, Z Xie, R Weiss ACS synthetic biology 4 (6), 673-681, 2015 | 77 | 2015 |
Safe CRISPR: challenges and possible solutions M Pineda, A Lear, JP Collins, S Kiani Trends in biotechnology 37 (4), 389-401, 2019 | 66 | 2019 |
Nitric oxide: a new concept in chronic sinusitis pathogenesis M Naraghi, AF Deroee, MR Ebrahimkhani, S Kiani, AR Dehpour American journal of otolaryngology 28 (5), 334-337, 2007 | 64 | 2007 |
The synergistic anticonvulsant effect of agmatine and morphine: possible role of alpha 2-adrenoceptors K Riazi, H Honar, H Homayoun, N Rashidi, S Kiani, MR Ebrahimkhani, ... Epilepsy research 65 (1-2), 33-40, 2005 | 40 | 2005 |
Engineered CRISPR systems for next generation gene therapies M Pineda, F Moghadam, MR Ebrahimkhani, S Kiani ACS synthetic biology 6 (9), 1614-1626, 2017 | 38 | 2017 |
Approaches to reduce CRISPR off-target effects for safer genome editing JE Chapman, D Gillum, S Kiani Applied Biosafety 22 (1), 7-13, 2017 | 38 | 2017 |
Synthetic immunomodulation with a CRISPR super-repressor in vivo F Moghadam, R LeGraw, JJ Velazquez, NC Yeo, C Xu, J Park, A Chavez, ... Nature cell biology 22 (9), 1143-1154, 2020 | 32 | 2020 |
Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing M Angrist, R Barrangou, F Baylis, C Brokowski, G Burgio, A Caplan, ... The CRISPR journal 3 (5), 332-349, 2020 | 28 | 2020 |
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis MR Ebrahimkhani, H Sadeghipour, M Dehghani, S Kiani, S Payabvash, ... Life sciences 76 (21), 2497-2512, 2005 | 28 | 2005 |