Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo S Philippe, C Sarkis, M Barkats, H Mammeri, C Ladroue, C Petit, J Mallet, ... Proceedings of the National Academy of Sciences 103 (47), 17684-17689, 2006 | 329 | 2006 |
The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain V Zennou, C Serguera, C Sarkis, P Colin, E Perret, J Mallet, P Charneau Nature biotechnology 19 (5), 446-450, 2001 | 267 | 2001 |
Efficient transduction of neural cells in vitro and in vivo by a baculovirus-derived vector C Sarkis, C Serguera, S Petres, D Buchet, JL Ridet, L Edelman, J Mallet Proceedings of the National Academy of Sciences 97 (26), 14638-14643, 2000 | 248 | 2000 |
Expression of GDNF transgene in astrocytes improves cognitive deficits in aged rats M Pertusa, S Garcia-Matas, H Mammeri, A Adell, T Rodrigo, J Mallet, ... Neurobiology of Aging 29 (9), 1366-1379, 2008 | 139 | 2008 |
Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction R El-Khoury, E Dufour, M Rak, N Ramanantsoa, N Grandchamp, Z Csaba, ... PLoS genetics 9 (1), e1003182, 2013 | 132 | 2013 |
Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity C Couturier, C Sarkis, K Séron, S Belouzard, P Chen, A Lenain, L Corset, ... Proceedings of the National Academy of Sciences 104 (49), 19476-19481, 2007 | 122 | 2007 |
Lenti‐GDNF gene therapy protects against Alzheimer's disease‐like neuropathology in 3xTg‐AD mice and MC65 cells S Revilla, S Ursulet, MJ Álvarez‐López, M Castro‐Freire, U Perpiñá, ... CNS neuroscience & therapeutics 20 (11), 961-972, 2014 | 121 | 2014 |
SIRT1 overexpression in mouse hippocampus induces cognitive enhancement through proteostatic and neurotrophic mechanisms R Corpas, S Revilla, S Ursulet, M Castro-Freire, P Kaliman, V Petegnief, ... Molecular neurobiology 54, 5604-5619, 2017 | 115 | 2017 |
Non-integrating lentiviral vectors C Sarkis, S Philippe, J Mallet, C Serguera Current gene therapy 8 (6), 430-437, 2008 | 97 | 2008 |
Neurodegenerative diseases: neurobiology, pathogenesis and therapeutics MF Beal, AE Lang, AC Ludolph Cambridge University Press, 2005 | 78 | 2005 |
CRE and TRE sequences of the rat tyrosine hydroxylase promoter are required for TH basal expression in adult mice but not in the embryo C Trocmé, C Sarkis, JM Hermel, R Duchateau, S Harrison, M Simonneau, ... European Journal of Neuroscience 10 (2), 508-521, 1998 | 76 | 1998 |
Retinal cell type expression specificity of HIV‐1‐derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter AP Bemelmans, S Bonnel, L Houhou, N Dufour, E Nandrot, D Helmlinger, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 60 | 2005 |
Retinal degeneration progression changes lentiviral vector cell targeting in the retina M Calame, M Cachafeiro, S Philippe, K Schouwey, M Tekaya, D Wanner, ... PloS one 6 (8), e23782, 2011 | 37 | 2011 |
Transplantation of human adult astrocytes: efficiency and safety requirements for an autologous gene therapy JL Ridet, C Sarkis, C Serguera, V Zennou, P Charneau, J Mallet Journal of neuroscience research 72 (6), 704-708, 2003 | 28 | 2003 |
Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice V Vauthier, TD Swartz, P Chen, C Roujeau, M Pagnon, J Mallet, C Sarkis, ... Gene Therapy 21 (7), 638-644, 2014 | 25 | 2014 |
Primary adult human astrocytes as an ex vivo vehicle for β-glucuronidase delivery in the brain C Serguera, C Sarkis, JL Ridet, P Colin, P Moullier, J Mallet Molecular Therapy 3 (6), 875-881, 2001 | 25 | 2001 |
Non-integrative and non-replicative lentivirus, preparation and uses thereof J Mallet, C Serguera, S Philippe, C Sarkis US Patent 8,119,119, 2012 | 24 | 2012 |
Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy C Kostic, SG Lillico, SV Crippa, N Grandchamp, H Pilet, S Philippe, Z Lu, ... PLoS One 8 (8), e71363, 2013 | 20 | 2013 |
Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors N Grandchamp, D Henriot, S Philippe, L Amar, S Ursulet, C Serguera, ... Genetic vaccines and therapy 9, 1-8, 2011 | 18 | 2011 |
Sodium butyrate modifies the stabilizing complexes of tyrosine hydroxylase mRNA T Aranyi, C Sarkis, S Berrard, K Sardin, V Siron, O Khalfallah, J Mallet Biochemical and biophysical research communications 359 (1), 15-19, 2007 | 18 | 2007 |