Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells A Rice, E Cortes Oncogenesis, 2017 | 549 | 2017 |
ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion A Chronopoulos, B Robinson, M Sarper, E Cortes, V Auernheimer, ... Nature communications 7 (1), 12630, 2016 | 267 | 2016 |
FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis D Lachowski, E Cortes, B Robinson, A Rice, K Rombouts, ... The FASEB Journal 32 (2), 1099-1107, 2018 | 190 | 2018 |
Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis D Lachowski, E Cortes, A Rice, D Pinato, K Rombouts, ... Scientific reports 9 (1), 7299, 2019 | 146 | 2019 |
Substrate rigidity controls activation and durotaxis in pancreatic stellate cells D Lachowski, E Cortes, D Pink, A Chronopoulos, SA Karim, J P. Morton, ... Scientific reports 7 (1), 2506, 2017 | 135 | 2017 |
Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway VPHAERH Antonios Chronopoulos, Stephen D. Thorpe, Ernesto Cortes, Dariusz ... Nature Materials, 2020 | 95 | 2020 |
Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival E Cortes, D Lachowski, B Robinson, M Sarper, JS Teppo, SD Thorpe, ... EMBO reports 20 (1), e46557, 2019 | 84 | 2019 |
ATRA modulates mechanical activation of TGF-β by pancreatic stellate cells M Sarper, E Cortes, TJ Lieberthal, A del Río Hernández Scientific reports 6 (1), 27639, 2016 | 84 | 2016 |
Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment JGARH Simon J. Attwood, Ernesto Cortes, Alexander William M. Haining ... Scientific Report, 2016 | 81 | 2016 |
GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment E Cortes, M Sarper, B Robinson, D Lachowski, A Chronopoulos, ... EMBO reports 20 (1), e46556, 2019 | 76 | 2019 |
Mechanotransduction in talin through the interaction of the R8 domain with DLC1 AWM Haining, R Rahikainen, E Cortes, D Lachowski, A Rice, ... PLoS biology 16 (7), e2005599, 2018 | 72 | 2018 |
Retinoic acid receptor‐β is downregulated in hepatocellular carcinoma and cirrhosis and its expression inhibits myosin‐driven activation and durotaxis in hepatic stellate cells E Cortes, D Lachowski, A Rice, A Chronopoulos, B Robinson, S Thorpe, ... Hepatology 69 (2), 785-802, 2019 | 67* | 2019 |
Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor E Cortes, D Lachowski, A Rice, SD Thorpe, B Robinson, G Yeldag, ... Oncogene 38 (16), 2910-2922, 2019 | 62 | 2019 |
Quantitative analysis of 3D extracellular matrix remodelling by pancreatic stellate cells ARH Benjamin K. Robinson, Ernesto Cortes, Alistair J. Rice, Muge Sarper Biology open, 2016 | 57 | 2016 |
Substrate Stiffness-Driven Membrane Tension Modulates Vesicular Trafficking via Caveolin-1 D Lachowski, C Matellan, S Gopal, E Cortes, BK Robinson, A Saiani, ... ACS nano 16 (3), 4322-4337, 2022 | 44 | 2022 |
GPER activation inhibits cancer cell mechanotransduction and basement membrane invasion via RhoA A Rice, E Cortes, D Lachowski, P Oertle, C Matellan, SD Thorpe, R Ghose, ... Cancers 12 (2), 289, 2020 | 24 | 2020 |
Self-assembling polypeptide hydrogels as a platform to recapitulate the tumor microenvironment D Lachowski, C Matellan, E Cortes, A Saiani, AF Miller, ... Cancers 13 (13), 3286, 2021 | 20 | 2021 |
Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2 C Matellan, D Lachowski, E Cortes, KN Chiam, A Krstic, SD Thorpe, ... Oncogenesis 12 (1), 23, 2023 | 14 | 2023 |
G protein-coupled estrogen receptor regulates actin cytoskeleton dynamics to impair cell polarization D Lachowski, E Cortes, C Matellan, A Rice, DA Lee, SD Thorpe, ... Frontiers in cell and developmental biology 8, 592628, 2020 | 14 | 2020 |
Implementation of a basement membrane invasion assay using mesenteric tissue R Ghose, AJ Rice, E Cortes, U Ghose, D Lachowski, A del Rio Hernandez Methods in Cell Biology 157, 99-122, 2020 | 4 | 2020 |