An atlas of genetic influences on osteoporosis in humans and mice JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Nature genetics 51 (2), 258-266, 2019 | 687 | 2019 |
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis JP Kemp, JA Morris, C Medina-Gomez, V Forgetta, NM Warrington, ... Nature genetics 49 (10), 1468, 2017 | 457 | 2017 |
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ... Cell 184 (5), 1330-1347. e13, 2021 | 335 | 2021 |
Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects C Medina-Gomez, JP Kemp, K Trajanoska, J Luan, A Chesi, TS Ahluwalia, ... The American Journal of Human Genetics 102 (1), 88-102, 2018 | 316 | 2018 |
Gene encoding a deubiquitinating enzyme is mutated in artesunate‐ and chloroquine‐resistant rodent malaria parasites§ P Hunt, A Afonso, A Creasey, R Culleton, ABS Sidhu, J Logan, ... Molecular microbiology 65 (1), 27-40, 2007 | 213 | 2007 |
Generation and culture of osteoclasts S Marino, JG Logan, D Mellis, M Capulli BoneKEy reports 3, 2014 | 143 | 2014 |
Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo GS Hönes, H Rakov, J Logan, XH Liao, E Werbenko, AS Pollard, ... Proceedings of the National Academy of Sciences 114 (52), E11323-E11332, 2017 | 124 | 2017 |
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease SE Youlten, JP Kemp, JG Logan, EJ Ghirardello, CM Sergio, MRG Dack, ... Nature communications 12 (1), 2444, 2021 | 93 | 2021 |
Accelerating functional gene discovery in osteoarthritis NC Butterfield, KF Curry, J Steinberg, H Dewhurst, D Komla-Ebri, ... Nature Communications 12 (1), 467, 2021 | 57 | 2021 |
Thyrostimulin regulates osteoblastic bone formation during early skeletal development JHD Bassett, A van der Spek, JG Logan, A Gogakos, ... Endocrinology 156 (9), 3098-3113, 2015 | 56 | 2015 |
Hydrogen sulphide‐releasing diclofenac derivatives inhibit breast cancer‐induced osteoclastogenesis in vitro and prevent osteolysis ex vivo J Frantzias, JG Logan, P Mollat, A Sparatore, P Del Soldato, SH Ralston, ... British journal of pharmacology 165 (6), 1914-1925, 2012 | 56 | 2012 |
Advanced bone formation in mice with a dominant-negative mutation in the thyroid hormone receptor β gene due to activation of Wnt/β-catenin protein signaling PJ O'Shea, DW Kim, JG Logan, S Davis, RL Walker, PS Meltzer, S Cheng, ... Journal of Biological Chemistry 287 (21), 17812-17822, 2012 | 48 | 2012 |
Slc20a2, Encoding the Phosphate Transporter PiT2, Is an Important Genetic Determinant of Bone Quality and Strength S Beck‐Cormier, CJ Lelliott, JG Logan, DT Lafont, L Merametdjian, ... Journal of Bone and Mineral Research 34 (6), 1101-1114, 2019 | 42 | 2019 |
Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast cancer-induced osteolysis A Sophocleous, S Marino, JG Logan, P Mollat, SH Ralston, AI Idris Journal of Biological Chemistry 290 (36), 22049-22060, 2015 | 38 | 2015 |
Rapid phenotyping of knockout mice to identify genetic determinants of bone strength B Freudenthal, J Logan, PI Croucher, GR Williams, JHD Bassett The Journal of endocrinology 231 (1), R31, 2016 | 31 | 2016 |
IGSF1 deficiency results in human and murine somatotrope neurosecretory hyperfunction SD Joustra, F Roelfsema, ASP van Trotsenburg, HJ Schneider, ... The Journal of Clinical Endocrinology & Metabolism 105 (3), e70-e84, 2020 | 30 | 2020 |
Mice lacking the calcineurin inhibitor Rcan2 have an isolated defect of osteoblast function JHD Bassett, JG Logan, A Boyde, MS Cheung, H Evans, P Croucher, ... Endocrinology 153 (7), 3537-3548, 2012 | 28 | 2012 |
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density AL Swan, C Schütt, J Rozman, M del Mar Muñiz Moreno, S Brandmaier, ... PLoS genetics 16 (12), e1009190, 2020 | 25 | 2020 |
A trans-eQTL network regulates osteoclast multinucleation and bone mass M Pereira, JH Ko, J Logan, H Protheroe, KB Kim, ALM Tan, PI Croucher, ... Elife 9, e55549, 2020 | 24 | 2020 |
Pharmacological inhibition of NFκB reduces prostate cancer related osteoclastogenesis in vitro and osteolysis ex vivo S Marino, RT Bishop, G Carrasco, JG Logan, B Li, AI Idris Calcified tissue international 105, 193-204, 2019 | 20 | 2019 |