| An enhanced CRISPR repressor for targeted mammalian gene regulation NC Yeo, A Chavez, A Lance-Byrne, Y Chan, D Menn, D Milanova, ... Nature methods 15 (8), 611-616, 2018 | 485 | 2018 |
| High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast X Guo, A Chavez, A Tung, Y Chan, C Kaas, Y Yin, R Cecchi, SL Garnier, ... Nature biotechnology 36 (6), 540-546, 2018 | 98 | 2018 |
| Accurate analysis of genuine CRISPR editing events with ampliCan K Labun, X Guo, A Chavez, G Church, JA Gagnon, E Valen Genome Research, 2019 | 67 | 2019 |
| Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction ML Kozak, A Chavez, W Dang, SL Berger, A Ashok, X Guo, FB Johnson The EMBO journal 29 (1), 158-170, 2010 | 65 | 2010 |
| Regulation of hetDNA length during mitotic double-strand break repair in yeast X Guo, YF Hum, K Lehner, S Jinks-Robertson Molecular cell 67 (4), 539-549. e4, 2017 | 40 | 2017 |
| SMRT sequencing for parallel analysis of multiple targets and accurate SNP phasing X Guo, K Lehner, K O’Connell, J Zhang, SS Dave, S Jinks-Robertson G3: Genes, Genomes, Genetics 5 (12), 2801-2808, 2015 | 32 | 2015 |
| Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder ET Lim, Y Chan, P Dawes, X Guo, S Erdin, DJC Tai, S Liu, JM Reichert, ... Nature Communications 13 (1), 3243, 2022 | 19 | 2022 |
| CRISPR guide RNA cloning for mammalian systems S Nageshwaran, A Chavez, NC Yeo, X Guo, A Lance-Byrne, A Tung, ... Journal of visualized experiments: JoVE, 2018 | 19 | 2018 |
| An integrated pipeline for mammalian genetic screening C Kramme, AM Plesa, HH Wang, B Wolf, MP Smela, X Guo, RE Kohman, ... Cell Reports Methods 1 (6), 2021 | 18 | 2021 |
| Enabling multiplexed testing of pooled donor cells through whole-genome sequencing Y Chan, YK Chan, DB Goodman, X Guo, A Chavez, ET Lim, GM Church Genome Medicine 10, 1-11, 2018 | 10 | 2018 |
| Roles of exonucleases and translesion synthesis DNA polymerases during mitotic gap repair in yeast X Guo, S Jinks-Robertson DNA repair 12 (12), 1024-1030, 2013 | 9 | 2013 |
| MegaGate: A toxin-less gateway molecular cloning tool C Kramme, AM Plesa, HH Wang, B Wolf, MP Smela, X Guo, RE Kohman, ... STAR protocols 2 (4), 100907, 2021 | 8 | 2021 |
| Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates X Guo, S Jinks-Robertson DNA repair 12 (12), 1053-1061, 2013 | 7 | 2013 |
| Role of the Srs2–Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae SS Jenkins, S Gore, X Guo, J Liu, C Ede, X Veaute, S Jinks-Robertson, ... Genetics 212 (4), 1133-1145, 2019 | 6 | 2019 |
| Identifying cell type specific driver genes in autism-associated copy number loci from cerebral organoids ET Lim, Y Chan, MJ Burns, X Guo, S Erdin, DJC Tai, JM Reichert, ... bioRxiv, 2020.11. 15.375386, 2020 | 5 | 2020 |
| High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9 X Guo, A Chavez, A Tung, Y Chan, R Cecchi, SL Garnier, C Kaas, ... bioRxiv, 2017 | 2 | 2017 |
| Generation and application of a versatile CRISPR toolkit for mammalian cell engineering N Dang, A Lance-Byrne, A Tung, X Guo, RJ Cecchi, J Buchthal, A Chavez, ... Synthetic Biology 6 (1), ysab033, 2021 | 1 | 2021 |
| Stampscreen: An integrated pipeline for mammalian genetic screening C Kramme, A Plesa, HH Wang, B Wolf, M Smela, X Guo, R Kohman, ... Available at SSRN 3875773, 0 | 1 | |
| Data integration of bulk and single-cell transcriptomics from cerebral organoids and post-mortem brains to identify cell types and cell type specific driver genes in autism E Lim, Y Chan, M Burns, X Guo, S Erdin, D Tai, J Reichert, YK Chan, ... | | 2020 |
| Methods of genetically altering yeast to produce yeast variants CS Kaas, A Chavez, X Guo WO Patent App. 62/396,395, 2018 | | 2018 |