CD28/B7 system of T cell costimulation DJ Lenschow, TL Walunas, JA Bluestone Annual review of immunology 14 (1), 233-258, 1996 | 3748 | 1996 |
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 EA Tivol, F Borriello, AN Schweitzer, WP Lynch, JA Bluestone, AH Sharpe Immunity 3 (5), 541-547, 1995 | 3733 | 1995 |
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells W Liu, AL Putnam, Z Xu-Yu, GL Szot, MR Lee, S Zhu, PA Gottlieb, ... The Journal of experimental medicine 203 (7), 1701-1711, 2006 | 3553 | 2006 |
CTLA-4 can function as a negative regulator of T cell activation TL Walunas, DJ Lenschow, CY Bakker, PS Linsley, GJ Freeman, ... Immunity 1 (5), 405-413, 1994 | 2826 | 1994 |
B7/CD28 costimulation is essential for the homeostasis of the CD4+ CD25+ immunoregulatory T cells that control autoimmune diabetes B Salomon, DJ Lenschow, L Rhee, N Ashourian, B Singh, A Sharpe, ... Immunity 12 (4), 431-440, 2000 | 2657 | 2000 |
International trial of the Edmonton protocol for islet transplantation AMJ Shapiro, C Ricordi, BJ Hering, H Auchincloss, R Lindblad, ... New England Journal of Medicine 355 (13), 1318-1330, 2006 | 2508 | 2006 |
Innate immunity and intestinal microbiota in the development of Type 1 diabetes L Wen, RE Ley, PY Volchkov, PB Stranges, L Avanesyan, AC Stonebraker, ... Nature 455 (7216), 1109-1113, 2008 | 2285 | 2008 |
Identification of a monoclonal antibody specific for a murine T3 polypeptide. O Leo, M Foo, DH Sachs, LE Samelson, JA Bluestone Proceedings of the National Academy of Sciences 84 (5), 1374-1378, 1987 | 2103 | 1987 |
Natural versus adaptive regulatory T cells JA Bluestone, AK Abbas Nature Reviews Immunology 3 (3), 253-257, 2003 | 2037 | 2003 |
The B7 and CD28 receptor families CH June, JA Bluestone, LM Nadler, CB Thompson Immunology today 15 (7), 321-331, 1994 | 1796 | 1994 |
Genetics, pathogenesis and clinical interventions in type 1 diabetes JA Bluestone, K Herold, G Eisenbarth Nature 464 (7293), 1293-1300, 2010 | 1651 | 2010 |
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo X Zhou, SL Bailey-Bucktrout, LT Jeker, C Penaranda, ... Nature immunology 10 (9), 1000-1007, 2009 | 1511 | 2009 |
In vitro–expanded antigen-specific regulatory T cells suppress autoimmune diabetes Q Tang, KJ Henriksen, M Bi, EB Finger, G Szot, J Ye, EL Masteller, ... The Journal of experimental medicine 199 (11), 1455-1465, 2004 | 1510 | 2004 |
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus KC Herold, W Hagopian, JA Auger, E Poumian-Ruiz, L Taylor, ... New England Journal of Medicine 346 (22), 1692-1698, 2002 | 1489 | 2002 |
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg DJ Lenschow, Y Zeng, JR Thistlethwaite, A Montag, W Brady, MG Gibson, ... Science 257 (5071), 789-792, 1992 | 1488 | 1992 |
The NOD mouse: a model of immune dysregulation MS Anderson, JA Bluestone Annu. Rev. Immunol. 23 (1), 447-485, 2005 | 1426 | 2005 |
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation B Salomon, JA Bluestone Annual review of immunology 19 (1), 225-252, 2001 | 1418 | 2001 |
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation Q Tang, JA Bluestone Nature immunology 9 (3), 239-244, 2008 | 1396 | 2008 |
Control of peripheral T‐cell tolerance and autoimmunity via the CTLA‐4 and PD‐1 pathways BT Fife, JA Bluestone Immunological reviews 224 (1), 166-182, 2008 | 1279 | 2008 |
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis N Komatsu, K Okamoto, S Sawa, T Nakashima, M Oh-Hora, T Kodama, ... Nature medicine 20 (1), 62-68, 2014 | 1230 | 2014 |