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Eicke Latz
Eicke Latz
Deutsches Rheuma-Forschungszentrum Berlin (DRFZ)
Bestätigte E-Mail-Adresse bei umassmed.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Neuroinflammation in Alzheimer's disease
MT Heneka, MJ Carson, J El Khoury, GE Landreth, F Brosseron, ...
The Lancet Neurology 14 (4), 388-405, 2015
60252015
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ...
Nature 464 (7293), 1357-1361, 2010
42652010
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
V Hornung, F Bauernfeind, A Halle, EO Samstad, H Kono, KL Rock, ...
Nature immunology 9 (8), 847-856, 2008
35132008
IKKε and TBK1 are essential components of the IRF3 signaling pathway
KA Fitzgerald, SM McWhirter, KL Faia, DC Rowe, E Latz, DT Golenbock, ...
Nature immunology 4 (5), 491-496, 2003
33522003
Activation and regulation of the inflammasomes
E Latz, TS Xiao, A Stutz
Nature Reviews Immunology 13 (6), 397-411, 2013
33112013
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ...
The Journal of Immunology 183 (2), 787-791, 2009
32292009
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
V Hornung, A Ablasser, M Charrel-Dennis, F Bauernfeind, G Horvath, ...
Nature 458 (7237), 514-518, 2009
29862009
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ...
Nature immunology 9 (8), 857-865, 2008
28632008
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
MT Heneka, MP Kummer, A Stutz, A Delekate, S Schwartz, ...
Nature 493 (7434), 674-678, 2013
28572013
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muñoz-Planillo, ...
Nature medicine 21 (3), 248-255, 2015
25772015
Trained immunity: a program of innate immune memory in health and disease
MG Netea, LAB Joosten, E Latz, KHG Mills, G Natoli, HG Stunnenberg, ...
Science 352 (6284), aaf1098, 2016
24582016
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
J Xue, SV Schmidt, J Sander, A Draffehn, W Krebs, I Quester, D De Nardo, ...
Immunity 40 (2), 274-288, 2014
23332014
Defining trained immunity and its role in health and disease
MG Netea, J Domínguez-Andrés, LB Barreiro, T Chavakis, M Divangahi, ...
Nature Reviews Immunology 20 (6), 375-388, 2020
21362020
IFI16 is an innate immune sensor for intracellular DNA
L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ...
Nature immunology 11 (11), 997-1004, 2010
19422010
Targeting the NLRP3 inflammasome in inflammatory diseases
MSJ Mangan, EJ Olhava, WR Roush, HM Seidel, GD Glick, E Latz
Nature reviews Drug discovery 17 (8), 588-606, 2018
18162018
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
E Latz, A Schoenemeyer, A Visintin, KA Fitzgerald, BG Monks, CF Knetter, ...
Nature immunology 5 (2), 190-198, 2004
17812004
Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
J Tian, AM Avalos, SY Mao, B Chen, K Senthil, H Wu, P Parroche, ...
Nature immunology 8 (5), 487-496, 2007
17052007
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the toll adapters TRAM and TRIF
KA Fitzgerald, DC Rowe, BJ Barnes, DR Caffrey, A Visintin, E Latz, ...
The Journal of experimental medicine 198 (7), 1043-1055, 2003
16492003
Innate immune activation in neurodegenerative disease
MT Heneka, MP Kummer, E Latz
Nature Reviews Immunology 14 (7), 463-477, 2014
15972014
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
VAK Rathinam, Z Jiang, SN Waggoner, S Sharma, LE Cole, L Waggoner, ...
Nature immunology 11 (5), 395-402, 2010
15572010
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