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Weijiao Huang
Weijiao Huang
UTSW
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Structural insights into µ-opioid receptor activation
W Huang, A Manglik, AJ Venkatakrishnan, T Laeremans, EN Feinberg, ...
Nature 524 (7565), 315-321, 2015
9372015
Structure of the neurotensin receptor 1 in complex with β-arrestin 1
W Huang, M Masureel, Q Qu, J Janetzko, A Inoue, HE Kato, MJ Robertson, ...
Nature 579 (7798), 303-308, 2020
3232020
Propagation of conformational changes during μ-opioid receptor activation
R Sounier, C Mas, J Steyaert, T Laeremans, A Manglik, W Huang, ...
Nature 524 (7565), 375-378, 2015
2702015
Conformational transitions of a neurotensin receptor 1–Gi1 complex
HE Kato, Y Zhang, H Hu, CM Suomivuori, FMN Kadji, J Aoki, ...
Nature 572 (7767), 80-85, 2019
2352019
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
W Huang, W Choi, W Hu, N Mi, Q Guo, M Ma, M Liu, Y Tian, P Lu, ...
Cell research 22 (3), 473-489, 2012
2242012
Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Y Wang, Y Huang, J Wang, C Cheng, W Huang, P Lu, YN Xu, P Wang, ...
Nature 462 (7272), 467-472, 2009
2142009
A proposed role for glutamine in cancer cell growth through acid resistance
W Huang, W Choi, Y Chen, Q Zhang, H Deng, W He, Y Shi
Cell research 23 (5), 724-727, 2013
992013
Insights into distinct signaling profiles of the µOR activated by diverse agonists
Q Qu, W Huang, D Aydin, JM Paggi, AB Seven, H Wang, S Chakraborty, ...
Nature chemical biology 19 (4), 423-430, 2023
742023
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor
M Korczynska, MJ Clark, C Valant, J Xu, EV Moo, S Albold, DR Weiss, ...
Proceedings of the National Academy of Sciences 115 (10), E2419-E2428, 2018
682018
Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and-C2
M Ma, JJ Liu, Y Li, Y Huang, N Ta, Y Chen, H Fu, MD Ye, Y Ding, ...
Cell research 27 (8), 989-1001, 2017
582017
Mechanistic insights into CED-4-mediated activation of CED-3
W Huang, T Jiang, W Choi, S Qi, Y Pang, Q Hu, Y Xu, X Gong, PD Jeffrey, ...
Genes & development 27 (18), 2039-2048, 2013
492013
Structure‐Based Evolution of G Protein‐Biased μ‐Opioid Receptor Agonists
H Wang, F Hetzer, W Huang, Q Qu, J Meyerowitz, J Kaindl, H Hübner, ...
Angewandte Chemie International Edition 61 (26), e202200269, 2022
452022
Structure of S1PR2–heterotrimeric G13 signaling complex
H Chen, K Chen, W Huang, LM Staudt, JG Cyster, X Li
Science Advances 8 (13), eabn0067, 2022
412022
Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
H Chen, W Huang, X Li
Structure 30 (7), 1016-1024. e5, 2022
202022
1, 3, 5-Triazine-cored maltoside amphiphiles for membrane protein extraction and stabilization
L Ghani, CF Munk, X Zhang, S Katsube, Y Du, C Cecchetti, W Huang, ...
Journal of the American Chemical Society 141 (50), 19677-19687, 2019
152019
Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization
HE Bae, C Cecchetti, Y Du, S Katsube, JS Mortensen, W Huang, S Rehan, ...
Acta biomaterialia 112, 250-261, 2020
142020
Author correction: Structural insights into μ-opioid receptor activation
W Huang, A Manglik, AJ Venkatakrishnan, T Laeremans, EN Feinberg, ...
Nature 584 (7820), E16-E16, 2020
82020
A µ-opioid receptor modulator that works cooperatively with naloxone
ES O’Brien, VA Rangari, A El Daibani, SO Eans, HR Hammond, E White, ...
Nature 631 (8021), 686-693, 2024
72024
Structural insights into distinct signaling profiles of the μOR activated by diverse agonists
Q Qu, W Huang, D Aydin, JM Paggi, AB Seven, H Wang, S Chakraborty, ...
Biorxiv, 2021.12. 07.471645, 2021
72021
Venkatakrishnan, a J
W Huang, A Manglik
Laeremans, T., Feinberg, EN, Sanborn, AL, Kato, HE, Livingston, KE, Thorsen …, 2015
62015
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