Structural insights into µ-opioid receptor activation W Huang, A Manglik, AJ Venkatakrishnan, T Laeremans, EN Feinberg, ... Nature 524 (7565), 315-321, 2015 | 937 | 2015 |
Structure of the neurotensin receptor 1 in complex with β-arrestin 1 W Huang, M Masureel, Q Qu, J Janetzko, A Inoue, HE Kato, MJ Robertson, ... Nature 579 (7798), 303-308, 2020 | 323 | 2020 |
Propagation of conformational changes during μ-opioid receptor activation R Sounier, C Mas, J Steyaert, T Laeremans, A Manglik, W Huang, ... Nature 524 (7565), 375-378, 2015 | 270 | 2015 |
Conformational transitions of a neurotensin receptor 1–Gi1 complex HE Kato, Y Zhang, H Hu, CM Suomivuori, FMN Kadji, J Aoki, ... Nature 572 (7767), 80-85, 2019 | 235 | 2019 |
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein W Huang, W Choi, W Hu, N Mi, Q Guo, M Ma, M Liu, Y Tian, P Lu, ... Cell research 22 (3), 473-489, 2012 | 224 | 2012 |
Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel Y Wang, Y Huang, J Wang, C Cheng, W Huang, P Lu, YN Xu, P Wang, ... Nature 462 (7272), 467-472, 2009 | 214 | 2009 |
A proposed role for glutamine in cancer cell growth through acid resistance W Huang, W Choi, Y Chen, Q Zhang, H Deng, W He, Y Shi Cell research 23 (5), 724-727, 2013 | 99 | 2013 |
Insights into distinct signaling profiles of the µOR activated by diverse agonists Q Qu, W Huang, D Aydin, JM Paggi, AB Seven, H Wang, S Chakraborty, ... Nature chemical biology 19 (4), 423-430, 2023 | 74 | 2023 |
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor M Korczynska, MJ Clark, C Valant, J Xu, EV Moo, S Albold, DR Weiss, ... Proceedings of the National Academy of Sciences 115 (10), E2419-E2428, 2018 | 68 | 2018 |
Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and-C2 M Ma, JJ Liu, Y Li, Y Huang, N Ta, Y Chen, H Fu, MD Ye, Y Ding, ... Cell research 27 (8), 989-1001, 2017 | 58 | 2017 |
Mechanistic insights into CED-4-mediated activation of CED-3 W Huang, T Jiang, W Choi, S Qi, Y Pang, Q Hu, Y Xu, X Gong, PD Jeffrey, ... Genes & development 27 (18), 2039-2048, 2013 | 49 | 2013 |
Structure‐Based Evolution of G Protein‐Biased μ‐Opioid Receptor Agonists H Wang, F Hetzer, W Huang, Q Qu, J Meyerowitz, J Kaindl, H Hübner, ... Angewandte Chemie International Edition 61 (26), e202200269, 2022 | 45 | 2022 |
Structure of S1PR2–heterotrimeric G13 signaling complex H Chen, K Chen, W Huang, LM Staudt, JG Cyster, X Li Science Advances 8 (13), eabn0067, 2022 | 41 | 2022 |
Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response H Chen, W Huang, X Li Structure 30 (7), 1016-1024. e5, 2022 | 20 | 2022 |
1, 3, 5-Triazine-cored maltoside amphiphiles for membrane protein extraction and stabilization L Ghani, CF Munk, X Zhang, S Katsube, Y Du, C Cecchetti, W Huang, ... Journal of the American Chemical Society 141 (50), 19677-19687, 2019 | 15 | 2019 |
Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization HE Bae, C Cecchetti, Y Du, S Katsube, JS Mortensen, W Huang, S Rehan, ... Acta biomaterialia 112, 250-261, 2020 | 14 | 2020 |
Author correction: Structural insights into μ-opioid receptor activation W Huang, A Manglik, AJ Venkatakrishnan, T Laeremans, EN Feinberg, ... Nature 584 (7820), E16-E16, 2020 | 8 | 2020 |
A µ-opioid receptor modulator that works cooperatively with naloxone ES O’Brien, VA Rangari, A El Daibani, SO Eans, HR Hammond, E White, ... Nature 631 (8021), 686-693, 2024 | 7 | 2024 |
Structural insights into distinct signaling profiles of the μOR activated by diverse agonists Q Qu, W Huang, D Aydin, JM Paggi, AB Seven, H Wang, S Chakraborty, ... Biorxiv, 2021.12. 07.471645, 2021 | 7 | 2021 |
Venkatakrishnan, a J W Huang, A Manglik Laeremans, T., Feinberg, EN, Sanborn, AL, Kato, HE, Livingston, KE, Thorsen …, 2015 | 6 | 2015 |