| Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ... Nature communications 3 (1), 708, 2012 | 925 | 2012 |
| Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 813 | 2014 |
| MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis J Mann, DCK Chu, A Maxwell, F Oakley, NL Zhu, H Tsukamoto, DA Mann Gastroenterology 138 (2), 705-714. e4, 2010 | 445 | 2010 |
| Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 434 | 2019 |
| Progress toward standardized diagnosis of vascular cognitive impairment: guidelines from the vascular impairment of cognition classification consensus study OA Skrobot, SE Black, C Chen, C DeCarli, T Erkinjuntti, GA Ford, ... Alzheimer's & Dementia 14 (3), 280-292, 2018 | 367 | 2018 |
| Multigenerational epigenetic adaptation of the hepatic wound-healing response M Zeybel, T Hardy, YK Wong, JC Mathers, CR Fox, A Gackowska, ... Nature medicine 18 (9), 1369-1377, 2012 | 318 | 2012 |
| Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis J Mann, F Oakley, F Akiboye, A Elsharkawy, AW Thorne, DA Mann Cell Death & Differentiation 14 (2), 275-285, 2007 | 296 | 2007 |
| Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ... Nature medicine 17 (12), 1668-1673, 2011 | 238 | 2011 |
| The vascular impairment of cognition classification consensus study OA Skrobot, J O'Brien, S Black, C Chen, C DeCarli, T Erkinjuntti, GA Ford, ... Alzheimer's & Dementia 13 (6), 624-633, 2017 | 227 | 2017 |
| Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease T Hardy, M Zeybel, CP Day, C Dipper, S Masson, S McPherson, ... Gut 66 (7), 1321-1328, 2017 | 222 | 2017 |
| Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis SFW Kendrick, G O'Boyle, J Mann, M Zeybel, J Palmer, DEJ Jones, ... Hepatology 51 (6), 1988-1997, 2010 | 199 | 2010 |
| IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts MI Suwara, NJ Green, LA Borthwick, J Mann, KD Mayer-Barber, L Barron, ... Mucosal immunology 7 (3), 684-693, 2014 | 195 | 2014 |
| A failure of transforming growth factor-β1 negative regulation maintains sustained NF-κB activation in gut inflammation G Monteleone, J Mann, I Monteleone, P Vavassori, R Bremner, M Fantini, ... Journal of Biological Chemistry 279 (6), 3925-3932, 2004 | 190 | 2004 |
| NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma CL Wilson, D Jurk, N Fullard, P Banks, A Page, S Luli, AM Elsharkawy, ... Nature communications 6 (1), 6818, 2015 | 186 | 2015 |
| The NF-κB p50: p50: HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes AM Elsharkawy, F Oakley, F Lin, G Packham, DA Mann, J Mann Journal of hepatology 53 (3), 519-527, 2010 | 186 | 2010 |
| Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis J Argemi, MU Latasa, SR Atkinson, IO Blokhin, V Massey, JP Gue, ... Nature communications 10 (1), 3126, 2019 | 178 | 2019 |
| Low-strength T-cell activation promotes Th17 responses HA Purvis, JN Stoop, J Mann, S Woods, AE Kozijn, S Hambleton, ... Blood, The Journal of the American Society of Hematology 116 (23), 4829-4837, 2010 | 178 | 2010 |
| A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse A Moles, L Murphy, CL Wilson, JB Chakraborty, C Fox, EJ Park, J Mann, ... Journal of hepatology 60 (4), 782-791, 2014 | 171 | 2014 |
| Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease M Zeybel, T Hardy, SM Robinson, C Fox, QM Anstee, T Ness, S Masson, ... Clinical epigenetics 7, 1-11, 2015 | 170 | 2015 |
| Transcriptional regulation of hepatic stellate cells J Mann, DA Mann Advanced drug delivery reviews 61 (7-8), 497-512, 2009 | 158 | 2009 |