New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids P Arukuusk, L Pärnaste, N Oskolkov, DM Copolovici, H Margus, K Padari, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (5), 1365-1373, 2013 | 98 | 2013 |
The formation of nanoparticles between small interfering RNA and amphipathic cell-penetrating peptides L Pärnaste, P Arukuusk, K Langel, T Tenson, Ü Langel Molecular Therapy-Nucleic Acids 7, 1-10, 2017 | 57 | 2017 |
Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide K Kurrikoff, KL Veiman, K Künnapuu, EM Peets, T Lehto, L Pärnaste, ... Scientific reports 7 (1), 17056, 2017 | 43 | 2017 |
Effects of cargo molecules on membrane perturbation caused by transportan10 based cell-penetrating peptides L Vasconcelos, F Madani, P Arukuusk, L Pärnaste, A Gräslund, Ü Langel Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (12), 3118-3129, 2014 | 38 | 2014 |
Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP L Porosk, P Arukuusk, K Põhako, K Kurrikoff, K Kiisholts, K Padari, ... Biomaterials science 7 (10), 4363-4374, 2019 | 35 | 2019 |
Tumor gene therapy by systemic delivery of plasmid DNA with cell‐penetrating peptides K Künnapuu, KL Veiman, L Porosk, E Rammul, K Kiisholts, Ü Langel, ... Faseb Bioadvances 1 (2), 105, 2018 | 34 | 2018 |
PepFects and NickFects for the intracellular delivery of nucleic acids P Arukuusk, L Pärnaste, M Hällbrink, Ü Langel Cell-Penetrating Peptides: Methods and Protocols, 303-315, 2015 | 34 | 2015 |
Approaches for the discovery of new cell-penetrating peptides L Porosk, I Gaidutšik, Ü Langel Expert Opinion on Drug Discovery 16 (5), 553-565, 2021 | 27 | 2021 |
Formulation of stable and homogeneous cell-penetrating peptide NF55 nanoparticles for efficient gene delivery in vivo K Freimann, P Arukuusk, K Kurrikoff, L Pärnaste, R Raid, A Piirsoo, ... Molecular Therapy-Nucleic Acids 10, 28-35, 2018 | 25 | 2018 |
Amyloid-like self-assembly of a hydrophobic cell-penetrating peptide and its use as a carrier for nucleic acids LR de Mello, L Porosk, TC Lourenço, BBM Garcia, CAR Costa, SW Han, ... ACS Applied Bio Materials 4 (8), 6404-6416, 2021 | 22 | 2021 |
Cell-penetrating peptide and siRNA-mediated therapeutic effects on endometriosis and cancer in vitro models K Kiisholts, K Kurrikoff, P Arukuusk, L Porosk, M Peters, A Salumets, ... Pharmaceutics 13 (10), 1618, 2021 | 18 | 2021 |
Methods to follow intracellular trafficking of cell-penetrating peptides L Pärnaste, P Arukuusk, E Zagato, K Braeckmans, Ü Langel Journal of Drug Targeting 24 (6), 508-519, 2016 | 18 | 2016 |
Approaches for evaluation of novel CPP-based cargo delivery systems L Porosk, Ü Langel Frontiers in Pharmacology 13, 1056467, 2022 | 13 | 2022 |
The development of cell-penetrating peptides for efficient and selective in vivo expression of mRNA in spleen tissue L Porosk, HH Härk, P Arukuusk, U Haljasorg, P Peterson, K Kurrikoff Pharmaceutics 15 (3), 952, 2023 | 11 | 2023 |
Predicting transiently expressed protein yields: Comparison of transfection methods in CHO and HEK293 L Porosk, J Nebogatova, HH Härk, B Vunk, P Arukuusk, U Toots, M Ustav, ... Pharmaceutics 14 (9), 1949, 2022 | 10 | 2022 |
Modification of the linker amino acid in the cell-penetrating peptide NickFect55 leads to enhanced pDNA transfection for in vivo applications HH Härk, L Porosk, LR de Mello, P Arukuusk, ER da Silva, K Kurrikoff Pharmaceutics 15 (3), 883, 2023 | 4 | 2023 |
Aggregation limiting cell-penetrating peptides derived from protein signal sequences L Porosk, HH Härk, RN Bicev, I Gaidutšik, J Nebogatova, EJ Armolik, ... International Journal of Molecular Sciences 24 (5), 4277, 2023 | 4 | 2023 |
Cell-penetrating peptides predicted from CASC3, AKIP1, and AHRR proteins L Porosk, K Põhako, P Arukuusk, Ü Langel Frontiers in Pharmacology 12, 716226, 2021 | 3 | 2021 |
Characterization of Peptide–Oligonucleotide Complexes Using Electron Microscopy, Dynamic Light Scattering, and Protease Resistance Assay K Padari, L Porosk, P Arukuusk, M Pooga Oligonucleotide-Based Therapies: Methods and Protocols, 127-139, 2019 | 3 | 2019 |
Endpoint and kinetic approaches for assessing transfection efficacy in mammalian cell culture L Porosk, J Nebogatova, I Gaidutšik, Ü Langel Cell Penetrating Peptides: Methods and Protocols, 529-545, 2022 | 2 | 2022 |