High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in … F Palacios, P Moreno, P Morande, C Abreu, A Correa, V Porro, AI Landoni, ... Blood, The Journal of the American Society of Hematology 115 (22), 4488-4496, 2010 | 125 | 2010 |
Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation F Palacios, C Abreu, D Prieto, P Morande, S Ruiz, T Fernandez-Calero, ... Leukemia 29 (1), 115-125, 2015 | 82 | 2015 |
Axonal mitochondrial clusters containing mutant SOD1 in transgenic models of ALS JR Sotelo-Silveira, P Lepanto, V Elizondo, S Horjales, F Palacios, ... Antioxidants & redox signaling 11 (7), 1535-1545, 2009 | 74 | 2009 |
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL G Ferrer, B Jung, PY Chiu, R Aslam, F Palacios, AN Mazzarello, ... Leukemia 35 (11), 3163-3175, 2021 | 42 | 2021 |
Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target F Palacios, XJ Yan, G Ferrer, SS Chen, S Vergani, X Yang, J Gardner, ... Leukemia 35 (4), 1037-1052, 2021 | 27 | 2021 |
Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment P Moreno, C Abreu, M Borge, F Palacios, P Morande, M Pegazzano, ... Leukemia 27 (3), 721-725, 2013 | 27 | 2013 |
Methylation status regulates lipoprotein lipase expression in chronic lymphocytic leukemia C Abreu, P Moreno, F Palacios, M Borge, P Morande, AI Landoni, ... Leukemia & lymphoma 54 (8), 1844-1848, 2013 | 22 | 2013 |
Dissecting chronic lymphocytic leukemia microenvironment signals in patients with unmutated disease: microRNA-22 regulates phosphatase and tensin homolog/AKT/FOXO1 pathway in … F Palacios, D Prieto, C Abreu, S Ruiz, P Morande, T Fernández-Calero, ... Leukemia & lymphoma 56 (5), 1560-1565, 2015 | 18 | 2015 |
AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms PE Morande, XJ Yan, J Sepulveda, N Seija, ME Marquez, N Sotelo, ... Blood, The Journal of the American Society of Hematology 138 (3), 246-258, 2021 | 12 | 2021 |
Chronic lymphocytic leukemia–like monoclonal B-cell lymphocytosis exhibits an increased inflammatory signature that is reduced in early-stage chronic lymphocytic leukemia G Blanco, A Puiggros, B Sherry, L Nonell, X Calvo, E Puigdecanet, ... Experimental Hematology 95, 68-80, 2021 | 11 | 2021 |
TGF-β/SMAD pathway is modulated by miR-26b-5p: Another piece in the puzzle of chronic lymphocytic leukemia progression ME Marquez, S Sernbo, E Payque, R Uria, JP Tosar, J Querol, C Berca, ... Cancers 14 (7), 1676, 2022 | 9 | 2022 |
Origins and consequences of AID expression in lymphoid neoplasms D Montamat-Sicotte, F Palacios, J M Di Noia, P Oppezzo Current Immunology Reviews 9 (2), 72-85, 2013 | 8 | 2013 |
CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: Apparent lack of central and early peripheral tolerance … S Vergani, D Bagnara, A Agathangelidis, AKY Ng, G Ferrer, ... Frontiers in oncology 13, 1112879, 2023 | 7 | 2023 |
Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia E Podaza, F Palacios, DO Croci, D Risnik, XJ Yan, MB Almejún, A Colado, ... haematologica 105 (9), e465, 2020 | 5 | 2020 |
An antibody‐based affinity chromatography tool to assess Cu, Zn superoxide dismutase (SOD) G93A structural complexity in vivo F Palacios, G Cota, S Horjales, A Lima, J Battistoni, J Sotelo‐Silveira, ... Biotechnology Journal 5 (3), 328-334, 2010 | 5 | 2010 |
Activated CLL cells regulate IL-17F–producing Th17 cells in miR155-dependent and outcome-specific manners B Jung, G Ferrer, PY Chiu, R Aslam, A Ng, F Palacios, M Wysota, ... JCI insight 7 (12), e158243, 2022 | 3 | 2022 |
Ibrutinib treatment reduces myeloid derived suppressor cell numbers and function in chronic lymphocytic leukemia G Ferrer, B Jung, A Rukhsana, PY Chiu, AN Mazzarello, F Palacios, ... Blood 132, 239, 2018 | 3 | 2018 |
B Cells of the Proliferative Fraction of CLL Clones Exhibit Activated B-Cell and Myeloid-Cell Signatures Suggesting Enhanced Antigen-Presentation, Integrin Responsiveness, and … XJ Yan, F Palacios, W Li, S Yancopoulos, C Calissano, JC Barrientos, ... Blood 128 (22), 302, 2016 | 3 | 2016 |
Microenvironment Interactions in Chronic Lymphocytic Leukemia: A Delicate Equilibrium Linking the Quiescent and the Proliferative Pool F Palacios, C Abreu, P Moreno, M Giordano, R Gamberale, P Oppezzo Chronic Lymphocytic Leukemia, 2012 | 3 | 2012 |
The RNA-binding protein musashi 2 is upregulated in the proliferative fraction of CLL clones, particularly in U-CLL patients, and its silencing induces programmed cell death F Palacios, XJ Yan, JC Barrientos, JE Kolitz, SL Allen, KR Rai, ... Blood 128 (22), 3216, 2016 | 2 | 2016 |