Adverse effects of doxorubicin and its metabolic product on cardiac RyR2 and SERCA2A AD Hanna, A Lam, S Tham, AF Dulhunty, NA Beard Molecular pharmacology 86 (4), 438-449, 2014 | 161 | 2014 |
Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle L Wei, AD Hanna, NA Beard, AF Dulhunty Cell calcium 45 (5), 474-484, 2009 | 79 | 2009 |
The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function S Pedrotti, J Giudice, A Dagnino-Acosta, M Knoblauch, RK Singh, ... Human molecular genetics 24 (8), 2360-2374, 2015 | 75 | 2015 |
A chemical chaperone improves muscle function in mice with a RyR1 mutation CS Lee, AD Hanna, H Wang, A Dagnino-Acosta, AD Joshi, M Knoblauch, ... Nature communications 8 (1), 14659, 2017 | 70 | 2017 |
Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to sustain muscle function CS Lee, A Dagnino-Acosta, V Yarotskyy, A Hanna, A Lyfenko, ... Skeletal muscle 5, 1-16, 2015 | 52 | 2015 |
MyoSight—semi-automated image analysis of skeletal muscle cross sections LW Babcock, AD Hanna, NH Agha, SL Hamilton Skeletal muscle 10, 1-11, 2020 | 34 | 2020 |
TRPV1 variants impair intracellular Ca2+ signaling and may confer susceptibility to malignant hyperthermia F Vanden Abeele, S Lotteau, S Ducreux, C Dubois, N Monnier, A Hanna, ... Genetics in Medicine 21 (2), 441-450, 2019 | 32 | 2019 |
Proteins within the intracellular calcium store determine cardiac R y R channel activity and cardiac output AF Dulhunty, E Wium, L Li, AD Hanna, S Mirza, S Talukder, NAA Ghazali, ... Clinical and Experimental Pharmacology and Physiology 39 (5), 477-484, 2012 | 32 | 2012 |
Multiple actions of the anthracycline daunorubicin on cardiac ryanodine receptors AD Hanna, M Janczura, E Cho, AF Dulhunty, NA Beard Molecular pharmacology 80 (3), 538-549, 2011 | 31 | 2011 |
Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function CS Lee, DK Georgiou, A Dagnino-Acosta, J Xu, II Ismailov, M Knoblauch, ... Journal of Biological Chemistry 289 (37), 25556-25570, 2014 | 27 | 2014 |
Regulation and dysregulation of cardiac ryanodine receptor (RyR2) open probability during diastole in health and disease AF Dulhunty, NA Beard, AD Hanna Journal of General Physiology 140 (2), 87-92, 2012 | 26 | 2012 |
Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation HJ Wang, CS Lee, RSZ Yee, L Groom, I Friedman, L Babcock, ... Nature Communications 11 (1), 5099, 2020 | 18 | 2020 |
Untargeted metabolomics profiling of skeletal muscle samples from malignant hyperthermia susceptible patients B Bojko, T Vasiljevic, E Boyaci, A Roszkowska, N Kraeva, CAI Moreno, ... Canadian journal of anaesthesia= Journal canadien d'anesthesie 68 (6), 761, 2021 | 17 | 2021 |
Cardiac ryanodine receptor activation by a high Ca2+ store load is reversed in a reducing cytoplasmic redox environment AD Hanna, A Lam, C Thekkedam, EM Gallant, NA Beard, AF Dulhunty Journal of cell science 127 (20), 4531-4541, 2014 | 16 | 2014 |
The anthracycline metabolite doxorubicinol abolishes RyR2 sensitivity to physiological changes in luminal Ca2+ through an interaction with calsequestrin AD Hanna, A Lam, C Thekkedam, H Willemse, AF Dulhunty, NA Beard Molecular pharmacology 92 (5), 576-587, 2017 | 13 | 2017 |
Pathological mechanisms of vacuolar aggregate myopathy arising from a Casq1 mutation AD Hanna, CS Lee, L Babcock, H Wang, J Recio, SL Hamilton FASEB journal: official publication of the Federation of American Societies …, 2021 | 5 | 2021 |
Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction MA Redd, Y Yoshikawa, N Khan, M Waqar, NJ Saez, JE Outhwaite, ... European Heart Journal 45 (17), 1571-1574, 2024 | 2 | 2024 |
Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads CS Lee, SY Jung, RSZ Yee, NH Agha, J Hong, T Chang, LW Babcock, ... Communications Biology 6 (1), 942, 2023 | 2 | 2023 |
Ryanodine receptor channelopathies in skeletal and cardiac muscle AD Hanna, LJ Sharp, SL Hamilton Ion Channels in Health and Disease, 53-84, 2016 | 2 | 2016 |
Correction: Cardiac ryanodine receptor activation by a high Ca2+ store load is reversed in a reducing cytoplasmic redox environment AD Hanna, A Lam, C Thekkedam, EM Gallant, NA Beard, AF Dulhunty J. Cell Sci 129 (22), 4317.10, 2016 | 1 | 2016 |