Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation CJ Tape, S Ling, M Dimitriadi, KM McMahon, JD Worboys, HS Leong, ... Cell 165 (4), 910-920, 2016 | 451 | 2016 |
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity JHL Fok, A Ramos-Montoya, M Vazquez-Chantada, PWG Wijnhoven, ... Nature communications 10 (1), 5065, 2019 | 292 | 2019 |
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models ST Durant, L Zheng, Y Wang, K Chen, L Zhang, T Zhang, Z Yang, ... Science advances 4 (6), eaat1719, 2018 | 285 | 2018 |
Pharmacology of the ATM inhibitor AZD0156: potentiation of irradiation and olaparib responses preclinically LC Riches, AG Trinidad, G Hughes, GN Jones, AM Hughes, ... Molecular cancer therapeutics 19 (1), 13-25, 2020 | 137 | 2020 |
Universal sample preparation unlocking multimodal molecular tissue imaging A Dannhorn, E Kazanc, S Ling, C Nikula, E Karali, MP Serra, JL Vorng, ... Analytical Chemistry 92 (16), 11080-11088, 2020 | 84 | 2020 |
Characterization of an aggregated three-dimensional cell culture model by multimodal mass spectrometry imaging LE Flint, G Hamm, JD Ready, S Ling, CJ Duckett, NA Cross, LM Cole, ... Analytical chemistry 92 (18), 12538-12547, 2020 | 59 | 2020 |
Method to visualize the intratumor distribution and impact of gemcitabine in pancreatic ductal adenocarcinoma by multimodal imaging N Strittmatter, FM Richards, AM Race, S Ling, D Sutton, A Nilsson, ... Analytical Chemistry 94 (3), 1795-1803, 2022 | 29 | 2022 |
Transforming early pharmaceutical assessment of genotoxicity: applying statistical learning to a high throughput, multi end point in vitro micronucleus assay A Wilson, P Grabowski, J Elloway, S Ling, J Stott, A Doherty Scientific reports 11 (1), 2535, 2021 | 21 | 2021 |
Multi-modal molecular imaging maps the correlation between tumor microenvironments and nanomedicine distribution N Strittmatter, JI Moss, AM Race, D Sutton, JR Canales, S Ling, E Wong, ... Theranostics 12 (5), 2162, 2022 | 16 | 2022 |
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models. Sci Adv. 2018; 4 (6): eaat1719 ST Durant, L Zheng, Y Wang, K Chen, L Zhang, T Zhang, Z Yang, ... Article PubMed PubMed Central CAS, 2022 | 14 | 2022 |
Evaluation of UV-C decontamination of clinical tissue sections for spatially resolved analysis by mass spectrometry imaging (MSI) A Dannhorn, S Ling, S Powell, E McCall, G Maglennon, GN Jones, ... Analytical Chemistry 93 (5), 2767-2775, 2021 | 10 | 2021 |
Comparison of osteosarcoma aggregated tumour models with human tissue by multimodal mass spectrometry imaging LE Flint, G Hamm, JD Ready, S Ling, CJ Duckett, NA Cross, LM Cole, ... Metabolites 11 (8), 506, 2021 | 8 | 2021 |
Holistic Characterization of a Salmonella Typhimurium Infection Model Using Integrated Molecular Imaging N Strittmatter, P Kanvatirth, P Inglese, AM Race, A Nilsson, A Dannhorn, ... Journal of the American Society for Mass Spectrometry 32 (12), 2791-2802, 2021 | 7 | 2021 |
Method to investigate the distribution of water-soluble drug-delivery systems in fresh frozen tissues using imaging mass cytometry N Strittmatter, RM England, AM Race, D Sutton, JI Moss, G Maglennon, ... Analytical Chemistry 93 (8), 3742-3749, 2021 | 6 | 2021 |
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function EO Asowata, S Romoli, R Sargeant, JY Tan, S Hoffmann, MM Huang, ... Kidney International 106 (1), 85-97, 2024 | 4 | 2024 |
Metabolic imaging across scales reveals distinct prostate cancer phenotypes N Sushentsev, G Hamm, L Flint, D Birtles, A Zakirov, J Richings, S Ling, ... Nature Communications 15 (1), 5980, 2024 | 3 | 2024 |
Intra-and intercellular signaling pathways associated with drug-induced cardiac pathophysiology F Guo, AR Hall, CJ Tape, S Ling, A Pointon Trends in pharmacological sciences 42 (8), 675-687, 2021 | 2 | 2021 |
Federation of Imaging Data for Life sciences: current status of metadata collection for high content screening, mass spectrometry imaging and light sheet microscopy of … F Brochu, E Cooke, M Romanchikova, J Bunch, A Dexter, R Steven, ... | 2 | 2020 |
Efficacy and pharmacodynamic effect of anti-CD73/PD-L1 monoclonal antibodies in combination with chemotherapy: observations from mouse tumor models J Eyles, A Watkins, K Ilieva, S Mullins, J Anderton, E Galvani, F Garcon, ... Cancer Research 81 (13_Supplement), 1584-1584, 2021 | 1 | 2021 |
Characterization of ATM inhibitor (AZD1390) distribution and pharmacodynamic changes in brain and glioblastoma in preclinical models to inform on mechanism of action L Oplustil O'Connor, G Hamm, M Udriste, S Ling, J Wilson, S Durant, ... Cancer Research 80 (16_Supplement), 6168-6168, 2020 | 1 | 2020 |