| Modeling formalisms in systems biology D Machado, RS Costa, M Rocha, EC Ferreira, B Tidor, I Rocha AMB Express 1 (1), 1-14, 2011 | 249 | 2011 |
| Galacto-oligosaccharides production during lactose hydrolysis by free Aspergillus oryzae β-galactosidase and immobilized on magnetic polysiloxane-polyvinyl alcohol DFM Neri, VM Balcão, RS Costa, ICAP Rocha, EMFC Ferreira, ... Food Chemistry 115 (1), 92-99, 2009 | 216 | 2009 |
| Hybrid dynamic modeling of Escherichia coli central metabolic network combining Michaelis-Menten and approximate kinetic equations RS Costa, D Machado, I Rocha, EC Ferrreira Biosystems 100 (2), 150-157, 2010 | 69 | 2010 |
| Toward community standards and software for whole-cell modeling D Waltemath, F Schreiber, JR Karr, CJ Myers, V Chelliah, ... IEEE Transactions on Biomedical Engineering 63 (10), 2016 | 65 | 2016 |
| Kinetic modeling of cell metabolism for microbial production RS Costa, A Hartmann, S Vinga Journal of biotechnology 219, 126-141, 2016 | 53 | 2016 |
| Identification of switched ARX models via convex optimization and expectation maximization A Hartmann, JM Lemos, RS Costa, J Xavier, S Vinga Journal of Process Control 28, 9-16, 2015 | 50 | 2015 |
| Exploring the gap between dynamic and constraint-based models of metabolism D Machado, RS Costa, EC Ferreira, I Rocha, B Tidor Metabolic engineering 14 (2), 112-119, 2012 | 49 | 2012 |
| KiMoSys: a web-based repository of experimental data for KInetic MOdels of biological SYStems RS Costa, A Veríssimo, S Vinga BMC Systems Biology 8 (1), 85, 2014 | 29 | 2014 |
| BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits A Dudnik, AF Almeida, R Andrade, B Avila, P Bañados, D Barbay, ... Phytochemistry reviews 17 (2), 291-326, 2018 | 27 | 2018 |
| Critical perspective on the consequences of the limited availability of kinetic data in metabolic dynamic modelling RS Costa, D Machado, I Rocha, EC Ferreira Systems Biology, IET 5 (3), 157-163, 2011 | 27 | 2011 |
| A general deep hybrid model for bioreactor systems: combining First Principles with deep neural networks J Pinto, M Mestre, J Ramos, RS Costa, G Striedner, R Oliveira Computers & Chemical Engineering 165, 107952, 2022 | 26 | 2022 |
| An extended dynamic model of Lactococcus lactis metabolism for mannitol and 2, 3-butanediol production RS Costa, A Hartmann, P Gaspar, AR Neves, S Vinga Molecular BioSystems 10 (3), 628-639, 2014 | 25 | 2014 |
| Root causes and outcomes of postoperative pulmonary complications after abdominal surgery: a retrospective observational cohort study A Fernandes, J Rodrigues, P Lages, S Lança, P Mendes, L Antunes, ... Patient Safety in Surgery 13 (1), 40, 2019 | 22 | 2019 |
| Implementation of a specific rate controller in a fed-batch E. coli fermentation I Rocha, ACA Veloso, S Carneiro, R Costa, EC Ferreira IFAC Proceedings Volumes 41 (2), 15565-15570, 2008 | 21 | 2008 |
| An Overview of Mathematical Modelling in Cancer Research: Fractional Calculus as Modelling Tool LC Vieira, RS Costa, D Valério Fractal and Fractional 7 (8), 595, 2023 | 17 | 2023 |
| Identifying IIR filter coefficients using particle swarm optimization with application to reconstruction of missing cardiovascular signals A Hartmann, JM Lemos, RS Costa, S Vinga Engineering Applications of Artificial Intelligence 34, 193-198, 2014 | 16 | 2014 |
| A critical review on modelling formalisms and simulation tools in computational biosystems D Machado, R Costa, M Rocha, I Rocha, B Tidor, E Ferreira Distributed Computing, Artificial Intelligence, Bioinformatics, Soft …, 2009 | 15 | 2009 |
| The relevance of enzyme specificity for coenzymes and the presence of 6-phosphogluconate dehydrogenase for polyhydroxyalkanoates production in the metabolism of Pseudomonas sp … J Cardinali-Rezende, A Di Genova, RA Nahat, A Steinbüchel, MF Sagot, ... International Journal of Biological Macromolecules 163, 240-250, 2020 | 14 | 2020 |
| Predictability of COVID-19 Hospitalizations, Intensive Care Unit Admissions, and Respiratory Assistance in Portugal: Longitudinal Cohort Study A Patrício, RS Costa*, R Henriques JMIR 23 (4), e26075, 2021 | 13 | 2021 |
| A General Hybrid Modeling Framework for Systems Biology Applications: Combining Mechanistic Knowledge with Deep Neural Networks under the SBML Standard J Pinto, JRC Ramos, RS Costa, R Oliveira AI 4 (1), 303-318, 2023 | 12 | 2023 |
