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Christopher Tape
Christopher Tape
Group Leader, University College London Cancer Institute
Bestätigte E-Mail-Adresse bei ucl.ac.uk - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
CJ Tape, S Ling, M Dimitriadi, K McMahon, JD Worboys, HS Leong, ...
Cell 165 (4), 2016
4512016
Thiol isomerases negatively regulate the cellular shedding activity of ADAM17
SH Willems, CJ Tape, PL Stanley, NA Taylor, IG Mills, DE Neal, ...
Biochemical Journal 428 (3), 439-450, 2010
2112010
Cross-domain inhibition of TACE ectodomain
CJ Tape, SH Willems, SL Dombernowsky, PL Stanley, M Fogarasi, ...
Proceedings of the National Academy of Sciences 108 (14), 5578-5583, 2011
1462011
Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis
R Natrajan, H Sailem, F Mardakheh, MA Garcia, CJ Tape, M Dowsett, ...
PLoS Medicine, 2016
1402016
Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance
JL Orgaz, E Crosas-Molist, A Sadok, A Perdrix-Rosell, O Maiques, ...
Cancer Cell 37 (1), 85-103. e9, 2020
1382020
Cell-type-specific signaling networks in heterocellular organoids
X Qin, J Sufi, P Vlckova, P Kyriakidou, SE Acton, VSW Li, M Nitz, CJ Tape
Nature methods 17 (3), 335-342, 2020
1252020
Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo
FM Richards, CJ Tape, DI Jodrell, G Murphy
PloS one 7 (7), e40597, 2012
1002012
Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination
M Montagner, R Bhome, S Hooper, P Chakravarty, X Qin, J Sufi, ...
Nature Cell Biology 22 (3), 289-296, 2020
992020
Fibroblastic reticular cells control conduit matrix deposition during lymph node expansion
VG Martinez, V Pankova, L Krasny, T Singh, S Makris, IJ White, ...
Cell reports 29 (9), 2810-2822. e5, 2019
932019
Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC
CJ Tape, JD Worboys, J Sinclair, R Gourlay, J Vogt, KM McMahon, ...
Analytical chemistry 86 (20), 10296-10302, 2014
892014
Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple-negative breast cancer cells
F Caiazza, PM McGowan, M Mullooly, A Murray, N Synnott, N O'Donovan, ...
British Journal of Cancer 112 (12), 1895-1903, 2015
762015
Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1 (A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of …
Y Huang, N Benaich, C Tape, HF Kwok, G Murphy
International journal of biological sciences 10 (7), 702, 2014
542014
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)
S Santamaria, K Yamamoto, K Botkjaer, C Tape, MR Dyson, J McCafferty, ...
Biochemical Journal 471 (3), 391-401, 2015
492015
An oncogenic phenoscape of colonic stem cell polarization
X Qin, FC Rodriguez, J Sufi, P Vlckova, J Claus, CJ Tape
Cell 186 (25), 5554-5568. e18, 2023
482023
Development of a ‘mouse and human cross-reactive’affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy
HF Kwok, KA Botkjaer, CJ Tape, Y Huang, J McCafferty, G Murphy
Protein Engineering, Design & Selection 27 (6), 179-190, 2014
402014
An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity
L Woodbine, S Grigoriadou, AA Goodarzi, E Riballo, C Tape, AW Oliver, ...
DNA repair 9 (9), 1003-1010, 2010
402010
Cell-specific labeling enzymes for analysis of cell–cell communication in continuous co-culture
CJ Tape, IC Norrie, JD Worboys, L Lim, DA Lauffenburger, C Jørgensen
Molecular & Cellular Proteomics 13 (7), 1866-1876, 2014
392014
Multiplexed single-cell analysis of organoid signaling networks
J Sufi, X Qin, FC Rodriguez, YJ Bu, P Vlckova, MR Zapatero, M Nitz, ...
Nature protocols 16 (10), 4897-4918, 2021
372021
Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses
MR Zapatero, A Tong, JW Opzoomer, R O’Sullivan, FC Rodriguez, J Sufi, ...
Cell 186 (25), 5606-5619. e24, 2023
352023
Systems biology analysis of heterocellular signaling
CJ Tape
Trends in biotechnology 34 (8), 627-637, 2016
342016
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