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sirintra nakjang
sirintra nakjang
Bioinformatician, Queen's University Belfast
Verificeret mail på qub.ac.uk
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År
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study
EC Schwalbe, JC Lindsey, S Nakjang, S Crosier, AJ Smith, D Hicks, ...
The Lancet Oncology 18 (7), 958-971, 2017
5292017
The Genome of the Obligate Intracellular Parasite Trachipleistophora hominis: New Insights into Microsporidian Genome Dynamics and Reductive Evolution
E Heinz, TA Williams, S Nakjang, CJ Noel, DC Swan, AV Goldberg, ...
PLoS pathogens 8 (10), e1002979, 2012
1692012
Reduction and expansion in microsporidian genome evolution: new insights from comparative genomics
S Nakjang, TA Williams, E Heinz, AK Watson, PG Foster, KM Sendra, ...
Genome biology and evolution 5 (12), 2285-2303, 2013
1582013
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma
RA Noble, N Bell, H Blair, A Sikka, H Thomas, N Phillips, S Nakjang, ...
Haematologica 102 (7), 1247, 2017
1332017
A novel extracellular metallopeptidase domain shared by animal host-associated mutualistic and pathogenic microbes
S Nakjang, DA Ndeh, A Wipat, DN Bolam, RP Hirt
PloS one 7 (1), e30287, 2012
1232012
Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes
C Alsmark, PG Foster, T Sicheritz-Ponten, S Nakjang, T Martin Embley, ...
Genome biology 14, 1-16, 2013
1092013
Trichomonas vaginalis pathobiology: new insights from the genome sequence
RP Hirt, N de Miguel, S Nakjang, D Dessi, YC Liu, N Diaz, P Rappelli, ...
Advances in parasitology 77, 87-140, 2011
1082011
The oncogenic transcription factor RUNX1/ETO corrupts cell cycle regulation to drive leukemic transformation
N Martinez-Soria, L McKenzie, J Draper, A Ptasinska, H Issa, S Potluri, ...
Cancer Cell 34 (4), 626-642. e8, 2018
1042018
Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites
E Heinz, C Hacker, P Dean, J Mifsud, AV Goldberg, TA Williams, ...
PLoS pathogens 10 (12), e1004547, 2014
1002014
Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
SA Freibert, AV Goldberg, C Hacker, S Molik, P Dean, TA Williams, ...
Nature Communications 8 (1), 13932, 2017
902017
Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites
P Dean, KM Sendra, TA Williams, AK Watson, P Major, S Nakjang, ...
Nature communications 9 (1), 1709, 2018
802018
Transport proteins of parasitic protists and their role in nutrient salvage
P Dean, P Major, S Nakjang, RP Hirt, TM Embley
Frontiers in plant science 5, 153, 2014
652014
Characterisation of the genomic landscape of CRLF2‐rearranged acute lymphoblastic leukemia
LJ Russell, L Jones, A Enshaei, S Tonin, SL Ryan, J Eswaran, S Nakjang, ...
Genes, Chromosomes and Cancer 56 (5), 363-372, 2017
632017
Chemical inhibition of wild-type p53-induced phosphatase 1 (WIP1/PPM1D) by GSK2830371 potentiates the sensitivity to MDM2 inhibitors in a p53-dependent manner
A Esfandiari, TA Hawthorne, S Nakjang, J Lunec
Molecular cancer therapeutics 15 (3), 379-391, 2016
572016
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities
E Kounatidou, S Nakjang, SRC McCracken, SM Dehm, CN Robson, ...
Nucleic acids research 47 (11), 5634-5647, 2019
542019
FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer
D Jones, M Wade, S Nakjang, L Chaytor, J Grey, CN Robson, L Gaughan
Oncotarget 6 (30), 29782, 2015
492015
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia
AS Gabriel, FM Lafta, EC Schwalbe, S Nakjang, SJ Cockell, A Iliasova, ...
Epigenetics 10 (8), 717-726, 2015
462015
Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia
R Tirtakusuma, K Szoltysek, P Milne, VV Grinev, A Ptasinska, PS Chin, ...
Blood, The Journal of the American Society of Hematology 140 (17), 1875-1890, 2022
452022
RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia
VV Grinev, F Barneh, IM Ilyushonak, S Nakjang, J Smink, A van Oort, ...
Nature communications 12 (1), 520, 2021
412021
The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival
UL McClurg, M Azizyan, DT Dransfield, N Namdev, NCTH Chit, S Nakjang, ...
Oncotarget 9 (38), 24992, 2018
392018
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Artikler 1–20