Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study EC Schwalbe, JC Lindsey, S Nakjang, S Crosier, AJ Smith, D Hicks, ... The Lancet Oncology 18 (7), 958-971, 2017 | 529 | 2017 |
The Genome of the Obligate Intracellular Parasite Trachipleistophora hominis: New Insights into Microsporidian Genome Dynamics and Reductive Evolution E Heinz, TA Williams, S Nakjang, CJ Noel, DC Swan, AV Goldberg, ... PLoS pathogens 8 (10), e1002979, 2012 | 169 | 2012 |
Reduction and expansion in microsporidian genome evolution: new insights from comparative genomics S Nakjang, TA Williams, E Heinz, AK Watson, PG Foster, KM Sendra, ... Genome biology and evolution 5 (12), 2285-2303, 2013 | 158 | 2013 |
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma RA Noble, N Bell, H Blair, A Sikka, H Thomas, N Phillips, S Nakjang, ... Haematologica 102 (7), 1247, 2017 | 133 | 2017 |
A novel extracellular metallopeptidase domain shared by animal host-associated mutualistic and pathogenic microbes S Nakjang, DA Ndeh, A Wipat, DN Bolam, RP Hirt PloS one 7 (1), e30287, 2012 | 123 | 2012 |
Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes C Alsmark, PG Foster, T Sicheritz-Ponten, S Nakjang, T Martin Embley, ... Genome biology 14, 1-16, 2013 | 109 | 2013 |
Trichomonas vaginalis pathobiology: new insights from the genome sequence RP Hirt, N de Miguel, S Nakjang, D Dessi, YC Liu, N Diaz, P Rappelli, ... Advances in parasitology 77, 87-140, 2011 | 108 | 2011 |
The oncogenic transcription factor RUNX1/ETO corrupts cell cycle regulation to drive leukemic transformation N Martinez-Soria, L McKenzie, J Draper, A Ptasinska, H Issa, S Potluri, ... Cancer Cell 34 (4), 626-642. e8, 2018 | 104 | 2018 |
Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites E Heinz, C Hacker, P Dean, J Mifsud, AV Goldberg, TA Williams, ... PLoS pathogens 10 (12), e1004547, 2014 | 100 | 2014 |
Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis SA Freibert, AV Goldberg, C Hacker, S Molik, P Dean, TA Williams, ... Nature Communications 8 (1), 13932, 2017 | 90 | 2017 |
Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites P Dean, KM Sendra, TA Williams, AK Watson, P Major, S Nakjang, ... Nature communications 9 (1), 1709, 2018 | 80 | 2018 |
Transport proteins of parasitic protists and their role in nutrient salvage P Dean, P Major, S Nakjang, RP Hirt, TM Embley Frontiers in plant science 5, 153, 2014 | 65 | 2014 |
Characterisation of the genomic landscape of CRLF2‐rearranged acute lymphoblastic leukemia LJ Russell, L Jones, A Enshaei, S Tonin, SL Ryan, J Eswaran, S Nakjang, ... Genes, Chromosomes and Cancer 56 (5), 363-372, 2017 | 63 | 2017 |
Chemical inhibition of wild-type p53-induced phosphatase 1 (WIP1/PPM1D) by GSK2830371 potentiates the sensitivity to MDM2 inhibitors in a p53-dependent manner A Esfandiari, TA Hawthorne, S Nakjang, J Lunec Molecular cancer therapeutics 15 (3), 379-391, 2016 | 57 | 2016 |
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities E Kounatidou, S Nakjang, SRC McCracken, SM Dehm, CN Robson, ... Nucleic acids research 47 (11), 5634-5647, 2019 | 54 | 2019 |
FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer D Jones, M Wade, S Nakjang, L Chaytor, J Grey, CN Robson, L Gaughan Oncotarget 6 (30), 29782, 2015 | 49 | 2015 |
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia AS Gabriel, FM Lafta, EC Schwalbe, S Nakjang, SJ Cockell, A Iliasova, ... Epigenetics 10 (8), 717-726, 2015 | 46 | 2015 |
Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia R Tirtakusuma, K Szoltysek, P Milne, VV Grinev, A Ptasinska, PS Chin, ... Blood, The Journal of the American Society of Hematology 140 (17), 1875-1890, 2022 | 45 | 2022 |
RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia VV Grinev, F Barneh, IM Ilyushonak, S Nakjang, J Smink, A van Oort, ... Nature communications 12 (1), 520, 2021 | 41 | 2021 |
The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival UL McClurg, M Azizyan, DT Dransfield, N Namdev, NCTH Chit, S Nakjang, ... Oncotarget 9 (38), 24992, 2018 | 39 | 2018 |