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Valentin Köhler
Valentin Köhler
senior scientist, permanent staff, University of Basel,
Verificeret mail på unibas.ch
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Artificial Metalloenzymes: Reaction Scope and Optimization Strategies
F Schwizer, Y Okamoto, T Heinisch, Y Gu, MM Pellizzoni, V Lebrun, ...
Chemical reviews 1 (118), 142-231, 2018
7352018
Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes
V Köhler, YM Wilson, M Dürrenberger, D Ghislieri, E Churakova, T Quinto, ...
Nature Chemistry 5 (2), 93-99, 2013
3762013
Cytochromes P450 as useful biocatalysts: addressing the limitations
E O'Reilly, V Köhler, SL Flitsch, NJ Turner
Chemical Communications 47 (9), 2490-2501, 2011
3102011
Enantioselective biocatalytic oxidative desymmetrization of substituted pyrrolidines
V Köhler, KR Bailey, A Znabet, J Raftery, M Helliwell, NJ Turner
Angew. Chem. Int. Ed 49 (12), 2182-2184, 2010
1712010
Highly stereoselective synthesis of substituted prolyl peptides using a combination of biocatalytic desymmetrization and multicomponent reactions
A Znabet, E Ruijter, FJJ de Kanter, V Köhler, M Helliwell, NJ Turner, ...
Angewandte Chemie 31 (122), 5417-5420, 2010
1482010
Artificial concurrent catalytic processes involving enzymes
V Köhler, NJ Turner
Chemical Communications 51 (3), 450-464, 2015
1352015
Chiral Boron‐Bridged Bisoxazolines: Readily Available Anionic Ligands for Asymmetric Catalysis
C Mazet, V Köhler, A Pfaltz
Angewandte Chemie International Edition 44 (31), 4888-4891, 2005
1152005
Efficient In Situ Regeneration of NADH Mimics by an Artificial Metalloenzyme
Y Okamoto, V Kohler, CE Paul, F Hollmann, TR Ward
ACS Catalysis 6 (6), 3553-3557, 2016
1092016
Improving the catalytic performance of an artificial metalloenzyme by computational design
T Heinisch, M Pellizzoni, M Dürrenberger, CE Tinberg, V Köhler, ...
Journal of the American Chemical Society 137 (32), 10414-10419, 2015
1052015
The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution
KE Atkin, R Reiss, V Koehler, KR Bailey, S Hart, JP Turkenburg, ...
Journal of molecular biology 384 (5), 1218-1231, 2008
1022008
Recent trends in biomimetic NADH regeneration
T Quinto, V Köhler, TR Ward
Topics in catalysis 57, 321-331, 2014
962014
Kinetic resolution of diols and pyridyl alcohols by Cu (II)(borabox)-catalyzed acylation
C Mazet, S Roseblade, V Köhler, A Pfaltz
Organic letters 8 (9), 1879-1882, 2006
962006
OsO4⋅ Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis‐Dihydroxylation of Olefins
V Köhler, J Mao, T Heinisch, A Pordea, A Sardo, YM Wilson, L Knörr, ...
Angewandte Chemie-International Edition 50 (46), 10863, 2011
932011
An NAD (P) H-dependent artificial transfer hydrogenase for multienzymatic cascades
Y Okamoto, V Kohler, TR Ward
Journal of the American Chemical Society 138 (18), 5781-5784, 2016
922016
Genetic optimization of the catalytic efficiency of artificial imine reductases based on biotin–streptavidin technology
F Schwizer, V Kohler, M Dürrenberger, L Knörr, TR Ward
ACS Catalysis 3 (8), 1752-1755, 2013
612013
Protein-based hybrid catalysts—design and evolution
V Köhler, YM Wilson, C Lo, A Sardo, TR Ward
Current opinion in biotechnology 21 (6), 744-752, 2010
542010
Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope
A Robin, V Köhler, A Jones, A Ali, PP Kelly, E O'Reilly, NJ Turner, ...
Beilstein journal of organic chemistry 7 (1), 1494-1498, 2011
502011
Radical biocatalysis: Using non-natural single electron transfer mechanisms to access new enzymatic functions
TK Hyster
Synlett 31 (03), 248-254, 2020
492020
Expanding the chemical diversity in artificial imine reductases based on the biotin–streptavidin technology
T Quinto, F Schwizer, JM Zimbron, A Morina, V Köhler, TR Ward
ChemCatChem 6 (4), 1010-1014, 2014
412014
First domino mukaiyama-aldol cyclizations of 1, 3-Bis (trimethylsiloxy)-1, 3-butadienes with 1, 2-diketones
P Langer, V Koehler
Organic Letters 2 (11), 1597-1599, 2000
372000
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Artikler 1–20