| Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2–STAT3 signaling pathway Y Dong, B Lu, X Zhang, J Zhang, L Lai, D Li, Y Wu, Y Song, J Luo, X Pang, ... Carcinogenesis 31 (12), 2097-2104, 2010 | 198 | 2010 |
| Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion T Zhang, J Li, Y Dong, D Zhai, L Lai, F Dai, H Deng, Y Chen, M Liu, Z Yi Breast cancer research and treatment 135, 445-458, 2012 | 120 | 2012 |
| Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2‐mediated JAK/STAT3 signaling in endothelial cell X Zhang, Y Song, Y Wu, Y Dong, L Lai, J Zhang, B Lu, F Dai, L He, M Liu, ... International journal of cancer 129 (10), 2502-2511, 2011 | 106 | 2011 |
| Aberrant FGFR tyrosine kinase signaling enhances the warburg effect by reprogramming LDH isoform expression and activity in prostate cancer J Liu, G Chen, Z Liu, S Liu, Z Cai, P You, Y Ke, L Lai, Y Huang, H Gao, ... Cancer research 78 (16), 4459-4470, 2018 | 102 | 2018 |
| Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor‐2 L Lai, J Liu, D Zhai, Q Lin, L He, Y Dong, J Zhang, B Lu, Y Chen, Z Yi, ... British journal of pharmacology 165 (4b), 1084-1096, 2012 | 98 | 2012 |
| Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2 Y Wang, J Dong, D Li, L Lai, S Siwko, Y Li, M Liu Stem cells 31 (9), 1921-1931, 2013 | 96 | 2013 |
| A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells F Dai, Y Chen, Y Song, L Huang, D Zhai, Y Dong, L Lai, T Zhang, D Li, ... PloS one 7 (12), e52162, 2012 | 88 | 2012 |
| LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells Z Yue, Z Yuan, L Zeng, Y Wang, L Lai, J Li, P Sun, X Xue, J Qi, Z Yang, ... The FASEB Journal 32 (5), 2422, 2018 | 73 | 2018 |
| Targeting pyruvate carboxylase by a small molecule suppresses breast cancer progression Q Lin, Y He, X Wang, Y Zhang, M Hu, W Guo, Y He, T Zhang, L Lai, Z Sun, ... Advanced Science 7 (9), 1903483, 2020 | 51 | 2020 |
| Glycolytic switch is required for transdifferentiation to endothelial lineage L Lai, E Reineke, DJ Hamilton, JP Cooke Circulation 139 (1), 119-133, 2019 | 43 | 2019 |
| PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis S Liu, L Lai, Q Zuo, F Dai, L Wu, Y Wang, Q Zhou, J Liu, J Liu, L Li, Q Lin, ... Journal of molecular and cellular cardiology 72, 28-38, 2014 | 41 | 2014 |
| 1′-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway X Pang, L Zhang, L Lai, J Chen, Y Wu, Z Yi, J Zhang, W Qu, BB Aggarwal, ... Carcinogenesis 32 (6), 904-912, 2011 | 36 | 2011 |
| Modulating DDAH/NOS pathway to discover vasoprotective insulin sensitizers L Lai, YT Ghebremariam Journal of diabetes research 2016 (1), 1982096, 2016 | 30 | 2016 |
| Lgr4 in ocular development and glaucoma S Siwko, L Lai, J Weng, M Liu Journal of Ophthalmology 2013 (1), 987494, 2013 | 13 | 2013 |
| Role of angiogenic transdifferentiation in vascular recovery JP Cooke, L Lai Frontiers in Cardiovascular Medicine 10, 1155835, 2023 | 7 | 2023 |
| Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload–induced angiogenesis JH Suh, L Lai, D Nam, J Kim, J Jo, GE Taffet, E Kim, JT Kaelber, HK Lee, ... Journal of Biological Chemistry 292 (52), 21643-21652, 2017 | 7 | 2017 |
| Plumbagin inhibits tumor angiogenesis and tumor growth through VEGFR2-mediated Ras signaling pathway L Lai, J Liu, D Zhai, Q Lin, L He, Y Dong, J Zhang, B Lu, Y Chen, Z Yi, ... Br. J. Pharmacol. doi 10, 2011 | 6 | 2011 |
| Epigenetic Regulation of Angiogenesis in Peripheral Artery Disease NK Malhi, KW Southerland, L Lai, ZB Chen Methodist DeBakey Cardiovascular Journal 19 (5), 47, 2023 | 5 | 2023 |
| Transflammation in tissue regeneration and response to injury: How cell-autonomous inflammatory signaling mediates cell plasticity JP Cooke, L Lai Advanced Drug Delivery Reviews 203, 115118, 2023 | 4 | 2023 |
| Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2–STAT3 signaling pathway Y Dong, B Lu, X Zhang, J Zhang, L Lai, D Li, Y Wu, Y Song, J Luo, X Pang, ... Carcin 33, 946, 2012 | 1 | 2012 |
John P CookeChair, Department of Cardiovascular Sciences, Houston Methodist Research InstituteVerificeret mail på houstonmethodist.org