Prostaglandins and leukotrienes: advances in eicosanoid biology CD Funk science 294 (5548), 1871-1875, 2001 | 4926 | 2001 |
Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase JT Huang, JS Welch, M Ricote, CJ Binder, TM Willson, C Kelly, JL Witztum, ... Nature 400 (6742), 378-382, 1999 | 1116 | 1999 |
Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease JZ Haeggstrom, CD Funk Chemical reviews 111 (10), 5866-5898, 2011 | 960 | 2011 |
Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment CD Funk, LB Funk, ME Kennedy, AS Pong, GA Fitzgerald The FASEB journal 5 (9), 2304-2312, 1991 | 826 | 1991 |
Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia YS Ho, JL Magnenat, RT Bronson, J Cao, M Gargano, M Sugawara, ... Journal of Biological Chemistry 272 (26), 16644-16651, 1997 | 747 | 1997 |
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice T Cyrus, JL Witztum, DJ Rader, R Tangirala, S Fazio, MRF Linton, ... The Journal of clinical investigation 103 (11), 1597-1604, 1999 | 661 | 1999 |
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and-2 by nonsteroidal anti-inflammatory drugs. O Laneuville, DK Breuer, DL Dewitt, T Hla, CD Funk, WL Smith Journal of Pharmacology and Experimental Therapeutics 271 (2), 927-934, 1994 | 617 | 1994 |
Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice M Mehrabian, H Allayee, J Wong, W Shih, XP Wang, Z Shaposhnik, ... Circulation research 91 (2), 120-126, 2002 | 549 | 2002 |
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene XS Chen, JR Shelter, EN Johnson, CD Funk Nature 372 (6502), 179-182, 1994 | 523 | 1994 |
Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor CRJ Kennedy, Y Zhang, S Brandon, Y Guan, K Coffee, CD Funk, ... Nature medicine 5 (2), 217-220, 1999 | 491 | 1999 |
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype. CD Funk, L Furci, GA FitzGerald, R Grygorczyk, C Rochette, MA Bayne, ... Journal of Biological Chemistry 268 (35), 26767-26772, 1993 | 442 | 1993 |
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm L Zhao, MPW Moos, R Gräbner, F Pédrono, J Fan, B Kaiser, N John, ... Nature medicine 10 (9), 966-973, 2004 | 430 | 2004 |
Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function Y Cheng, M Wang, Y Yu, J Lawson, CD Funk, GA FitzGerald The Journal of clinical investigation 116 (5), 1391-1399, 2006 | 426 | 2006 |
Leukotriene modifiers as potential therapeutics for cardiovascular disease CD Funk Nature Reviews Drug Discovery 4 (8), 664-672, 2005 | 419 | 2005 |
Molecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides. WC Song, CD Funk, AR Brash Proceedings of the National Academy of Sciences 90 (18), 8519-8523, 1993 | 399 | 1993 |
COX-2 inhibitors and cardiovascular risk CD Funk, GA FitzGerald Journal of cardiovascular pharmacology 50 (5), 470-479, 2007 | 396 | 2007 |
Effect of low-dose aspirin on vascular inflammation, plaque stability, and atherogenesis in low-density lipoprotein receptor–deficient mice T Cyrus, S Sung, L Zhao, CD Funk, S Tang, D Praticò Circulation 106 (10), 1282-1287, 2002 | 360 | 2002 |
The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice CD Funk Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1304 (1), 65-84, 1996 | 344 | 1996 |
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E–deficient mice T Cyrus, D Praticò, L Zhao, JL Witztum, DJ Rader, J Rokach, ... Circulation 103 (18), 2277-2282, 2001 | 319 | 2001 |
Molecular cloning and amino acid sequence of human 5-lipoxygenase. T Matsumoto, CD Funk, O Rådmark, JO Höög, H Jörnvall, B Samuelsson Proceedings of the National Academy of Sciences 85 (1), 26-30, 1988 | 300 | 1988 |