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Colin Funk
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Prostaglandins and leukotrienes: advances in eicosanoid biology
CD Funk
science 294 (5548), 1871-1875, 2001
49262001
Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
JT Huang, JS Welch, M Ricote, CJ Binder, TM Willson, C Kelly, JL Witztum, ...
Nature 400 (6742), 378-382, 1999
11161999
Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease
JZ Haeggstrom, CD Funk
Chemical reviews 111 (10), 5866-5898, 2011
9602011
Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment
CD Funk, LB Funk, ME Kennedy, AS Pong, GA Fitzgerald
The FASEB journal 5 (9), 2304-2312, 1991
8261991
Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia
YS Ho, JL Magnenat, RT Bronson, J Cao, M Gargano, M Sugawara, ...
Journal of Biological Chemistry 272 (26), 16644-16651, 1997
7471997
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice
T Cyrus, JL Witztum, DJ Rader, R Tangirala, S Fazio, MRF Linton, ...
The Journal of clinical investigation 103 (11), 1597-1604, 1999
6611999
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and-2 by nonsteroidal anti-inflammatory drugs.
O Laneuville, DK Breuer, DL Dewitt, T Hla, CD Funk, WL Smith
Journal of Pharmacology and Experimental Therapeutics 271 (2), 927-934, 1994
6171994
Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice
M Mehrabian, H Allayee, J Wong, W Shih, XP Wang, Z Shaposhnik, ...
Circulation research 91 (2), 120-126, 2002
5492002
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
XS Chen, JR Shelter, EN Johnson, CD Funk
Nature 372 (6502), 179-182, 1994
5231994
Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor
CRJ Kennedy, Y Zhang, S Brandon, Y Guan, K Coffee, CD Funk, ...
Nature medicine 5 (2), 217-220, 1999
4911999
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.
CD Funk, L Furci, GA FitzGerald, R Grygorczyk, C Rochette, MA Bayne, ...
Journal of Biological Chemistry 268 (35), 26767-26772, 1993
4421993
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm
L Zhao, MPW Moos, R Gräbner, F Pédrono, J Fan, B Kaiser, N John, ...
Nature medicine 10 (9), 966-973, 2004
4302004
Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
Y Cheng, M Wang, Y Yu, J Lawson, CD Funk, GA FitzGerald
The Journal of clinical investigation 116 (5), 1391-1399, 2006
4262006
Leukotriene modifiers as potential therapeutics for cardiovascular disease
CD Funk
Nature Reviews Drug Discovery 4 (8), 664-672, 2005
4192005
Molecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides.
WC Song, CD Funk, AR Brash
Proceedings of the National Academy of Sciences 90 (18), 8519-8523, 1993
3991993
COX-2 inhibitors and cardiovascular risk
CD Funk, GA FitzGerald
Journal of cardiovascular pharmacology 50 (5), 470-479, 2007
3962007
Effect of low-dose aspirin on vascular inflammation, plaque stability, and atherogenesis in low-density lipoprotein receptor–deficient mice
T Cyrus, S Sung, L Zhao, CD Funk, S Tang, D Praticò
Circulation 106 (10), 1282-1287, 2002
3602002
The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice
CD Funk
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1304 (1), 65-84, 1996
3441996
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E–deficient mice
T Cyrus, D Praticò, L Zhao, JL Witztum, DJ Rader, J Rokach, ...
Circulation 103 (18), 2277-2282, 2001
3192001
Molecular cloning and amino acid sequence of human 5-lipoxygenase.
T Matsumoto, CD Funk, O Rådmark, JO Höög, H Jörnvall, B Samuelsson
Proceedings of the National Academy of Sciences 85 (1), 26-30, 1988
3001988
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