Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples AF Hill, RJ Butterworth, S Joiner, G Jackson, MN Rossor, DJ Thomas, ... The Lancet 353 (9148), 183-189, 1999 | 894 | 1999 |
Location and properties of metal-binding sites on the human prion protein GS Jackson, I Murray, LLP Hosszu, N Gibbs, JP Waltho, AR Clarke, ... Proceedings of the National Academy of Sciences 98 (15), 8531-8535, 2001 | 649 | 2001 |
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations GS Jackson, LLP Hosszu, A Power, AF Hill, J Kenney, H Saibil, ... Science 283 (5409), 1935-1937, 1999 | 476 | 1999 |
Strain-specific prion-protein conformation determined by metal ions JDF Wadsworth, AF Hill, S Joiner, GS Jackson, AR Clarke, J Collinge Nature cell biology 1 (1), 55-59, 1999 | 375 | 1999 |
Disease-associated prion protein oligomers inhibit the 26S proteasome M Kristiansen, P Deriziotis, DE Dimcheff, GS Jackson, H Ovaa, ... Molecular cell 26 (2), 175-188, 2007 | 329 | 2007 |
Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding GS Jackson, RA Staniforth, DJ Halsall, T Atkinson, JJ Holbrook, ... Biochemistry 32 (10), 2554-2563, 1993 | 328 | 1993 |
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates A Dalrymple, EJ Wild, R Joubert, K Sathasivam, M Björkqvist, Å Petersén, ... Journal of proteome research 6 (7), 2833-2840, 2007 | 279 | 2007 |
Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay JA Edgeworth, M Farmer, A Sicilia, P Tavares, J Beck, T Campbell, ... The Lancet 377 (9764), 487-493, 2011 | 246 | 2011 |
Structural mobility of the human prion protein probed by backbone hydrogen exchange LLP Hosszu, NJ Baxter, GS Jackson, A Power, AR Clarke, JP Waltho, ... Nature structural biology 6 (8), 740-743, 1999 | 195 | 1999 |
Superoxide Dismutase 1 and tgSOD1G93A Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis R Chia, MH Tattum, S Jones, J Collinge, EMC Fisher, GS Jackson PloS one 5 (5), e10627, 2010 | 173 | 2010 |
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin S Cronier, N Gros, MH Tattum, GS Jackson, AR Clarke, J Collinge, ... Biochemical Journal 416 (2), 297-305, 2008 | 168 | 2008 |
Regional heterogeneity of cellular prion protein isoforms in the mouse brain V Beringue, G Mallinson, M Kaisar, M Tayebi, Z Sattar, G Jackson, ... Brain 126 (9), 2065-2073, 2003 | 167 | 2003 |
XAFS study of the high-affinity copper-binding site of human PrP91–231 and its low-resolution structure in solution SS Hasnain, LM Murphy, RW Strange, JG Grossmann, AR Clarke, ... Journal of molecular biology 311 (3), 467-473, 2001 | 159 | 2001 |
Interpreting small quantities of DNA: the hierarchy of propositions and the use of Bayesian networks IW Evett, PD Gill, G Jackson, J Whitaker, C Champod Journal of Forensic Sciences 47 (3), 520-530, 2002 | 157 | 2002 |
Multiple folding pathways for heterologously expressed human prion protein GS Jackson, AF Hill, C Joseph, L Hosszu, A Power, JP Waltho, AR Clarke, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999 | 157 | 1999 |
Crystal structure of human prion protein bound to a therapeutic antibody SV Antonyuk, CR Trevitt, RW Strange, GS Jackson, D Sangar, ... Proceedings of the National Academy of Sciences 106 (8), 2554-2558, 2009 | 154 | 2009 |
Expressing evaluative opinions: a position statement CEH Berger, J Buckleton, C Champod, IW Evett, G Jackson Sci Justice 51 (1), 1-2, 2011 | 147 | 2011 |
The role of the cellular prion protein in the immune system JD Isaacs, GS Jackson, DM Altmann Clinical & Experimental Immunology 146 (1), 1-8, 2006 | 143 | 2006 |
Mammalian prion proteins GS Jackson, AR Clarke Current opinion in structural biology 10 (1), 69-74, 2000 | 117 | 2000 |
An enzyme–detergent method for effective prion decontamination of surgical steel GS Jackson, E McKintosh, E Flechsig, K Prodromidou, P Hirsch, ... Journal of general virology 86 (3), 869-878, 2005 | 115 | 2005 |