| LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption J Luo, Z Yang, Y Ma, Z Yue, H Lin, G Qu, J Huang, W Dai, C Li, C Zheng, ... Nature medicine 22 (5), 539-546, 2016 | 351 | 2016 |
| Dual base editor catalyzes both cytosine and adenine base conversions in human cells X Zhang, B Zhu, L Chen, L Xie, W Yu, Y Wang, L Li, S Yin, L Yang, H Hu, ... Nature biotechnology 38 (7), 856-860, 2020 | 234 | 2020 |
| Genome-wide transcriptome profiling of homologous recombination DNA repair G Peng, C Chun-Jen Lin, W Mo, H Dai, YY Park, SM Kim, Y Peng, Q Mo, ... Nature communications 5 (1), 1-11, 2014 | 230 | 2014 |
| Inhibition of Rspo-Lgr4 facilitates checkpoint blockade therapy by switching macrophage polarization B Tan, X Shi, J Zhang, J Qin, N Zhang, H Ren, M Qian, S Siwko, ... Cancer research 78 (17), 4929-4942, 2018 | 147 | 2018 |
| GPR116, an adhesion G-protein–coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway X Tang, R Jin, G Qu, X Wang, Z Li, Z Yuan, C Zhao, S Siwko, T Shi, ... Cancer research 73 (20), 6206-6218, 2013 | 117 | 2013 |
| Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2 Y Wang, J Dong, D Li, L Lai, S Siwko, Y Li, M Liu Stem cells 31 (9), 1921-1931, 2013 | 96 | 2013 |
| Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants L Yang, X Zhang, L Wang, S Yin, B Zhu, L Xie, Q Duan, H Hu, R Zheng, ... Protein & cell 9 (9), 814-819, 2018 | 91 | 2018 |
| The role of GPCRs in bone diseases and dysfunctions J Luo, P Sun, S Siwko, M Liu, J Xiao Bone research 7 (1), 1-19, 2019 | 88 | 2019 |
| Evidence That an Early Pregnancy Causes a Persistent Decrease in the Number of Functional Mammary Epithelial Stem Cells—Implications for Pregnancy‐Induced Protection Against … SK Siwko, J Dong, MT Lewis, H Liu, SG Hilsenbeck, Y Li Stem Cells 26 (12), 3205-3209, 2008 | 84 | 2008 |
| Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer W Lu, W Yu, J He, W Liu, J Yang, X Lin, Y Zhang, X Wang, W Jiang, J Luo, ... EMBO molecular medicine 13 (1), e12798, 2021 | 76 | 2021 |
| LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells Z Yue, Z Yuan, L Zeng, Y Wang, L Lai, J Li, P Sun, X Xue, J Qi, Z Yang, ... The FASEB Journal 32 (5), 2422-2437, 2018 | 73 | 2018 |
| Dual Targeting of Bile Acid Receptor‐1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen‐Dependent Bone Loss in Mice Z Li, J Huang, F Wang, W Li, X Wu, C Zhao, J Zhao, H Wei, Z Wu, M Qian, ... Journal of Bone and Mineral Research 34 (4), 765-776, 2019 | 66 | 2019 |
| Lgr4 is a key regulator of prostate development and prostate stem cell differentiation W Luo, M Rodriguez, JM Valdez, X Zhu, K Tan, D Li, S Siwko, L Xin, M Liu Stem cells 31 (11), 2492-2505, 2013 | 64 | 2013 |
| PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB M Rodriguez, W Luo, J Weng, L Zeng, Z Yi, S Siwko, M Liu Oncogenesis 3 (8), e114-e114, 2014 | 56 | 2014 |
| Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors SK Siwko, W Bu, C Gutierrez, B Lewis, M Jechlinger, B Schaffhausen, Y Li Neoplasia 10 (7), 653-IN1, 2008 | 52 | 2008 |
| Engineering of a bona fide light-operated calcium channel L He, L Wang, H Zeng, P Tan, G Ma, S Zheng, Y Li, L Sun, F Dou, S Siwko, ... Nature communications 12 (1), 1-11, 2021 | 48 | 2021 |
| KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis SG Cho, D Li, K Tan, SK Siwko, M Liu Cancer and Metastasis Reviews 31 (3), 585-591, 2012 | 47 | 2012 |
| Repression of mammalian target of rapamycin complex 1 inhibits intestinal regeneration in acute inflammatory bowel disease models Y Guan, L Zhang, X Li, X Zhang, S Liu, N Gao, L Li, G Gao, G Wei, Z Chen, ... The Journal of Immunology 195 (1), 339-346, 2015 | 46 | 2015 |
| RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis Z Yue, X Niu, Z Yuan, Q Qin, W Jiang, L He, J Gao, Y Ding, Y Liu, Z Xu, ... The Journal of Clinical Investigation 132 (2), 2022 | 44 | 2022 |
| G-protein coupled receptor 124 (GPR124) in endothelial cells regulates vascular endothelial growth factor (VEGF)-induced tumor angiogenesis Y Wang, SG Cho, X Wu, S Siwko, M Liu Current molecular medicine 14 (4), 543-554, 2014 | 42 | 2014 |
