Pan-cancer analysis of whole genomes TITPCAWG Consortium Nature 578 (7793), 82, 2020 | 1919* | 2020 |
Pathway enrichment analysis and visualization of omics data using g: Profiler, GSEA, Cytoscape and EnrichmentMap J Reimand, R Isserlin, V Voisin, M Kucera, C Tannus-Lopes, ... Nature protocols 14 (2), 482-517, 2019 | 1595 | 2019 |
g: Profiler—a web-based toolset for functional profiling of gene lists from large-scale experiments J Reimand, M Kull, H Peterson, J Hansen, J Vilo Nucleic acids research 35 (suppl_2), W193-W200, 2007 | 1457 | 2007 |
g: Profiler—a web server for functional interpretation of gene lists (2016 update) J Reimand, T Arak, P Adler, L Kolberg, S Reisberg, H Peterson, J Vilo Nucleic acids research 44 (W1), W83-W89, 2016 | 1394 | 2016 |
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 1153 | 2015 |
Intertumoral heterogeneity within medulloblastoma subgroups FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ... Cancer cell 31 (6), 737-754. e6, 2017 | 1132 | 2017 |
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 996 | 2012 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 885 | 2016 |
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 834 | 2014 |
Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 770 | 2018 |
g: Profiler—a web server for functional interpretation of gene lists (2011 update) J Reimand, T Arak, J Vilo Nucleic acids research 39 (suppl_2), W307-W315, 2011 | 575 | 2011 |
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 568 | 2020 |
Comprehensive identification of mutational cancer driver genes across 12 tumor types D Tamborero, A Gonzalez-Perez, C Perez-Llamas, J Deu-Pons, ... Scientific reports 3 (1), 2650, 2013 | 555 | 2013 |
Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia, J Reimand, M Haider, ... Cell 164 (1), 293-309, 2016 | 471 | 2016 |
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity M Meyer, J Reimand, X Lan, R Head, X Zhu, M Kushida, J Bayani, ... Proceedings of the National Academy of Sciences 112 (3), 851-856, 2015 | 434 | 2015 |
Pathway and network analysis of cancer genomes P Creixell, J Reimand, S Haider, G Wu, T Shibata, M Vazquez, ... Nature methods 12 (7), 615, 2015 | 380* | 2015 |
Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 353 | 2016 |
Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers J Reimand, GD Bader Molecular systems biology 9 (1), 637, 2013 | 316 | 2013 |
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders L Uusküla-Reimand, H Hou, P Samavarchi-Tehrani, MV Rudan, M Liang, ... Genome biology 17, 1-22, 2016 | 253 | 2016 |
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 207 | 2018 |