Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease DJ Polhemus, DJ Lefer Circulation research 114 (4), 730-737, 2014 | 519 | 2014 |
Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent AL King, DJ Polhemus, S Bhushan, H Otsuka, K Kondo, CK Nicholson, ... Proceedings of the National Academy of Sciences 111 (8), 3182-3187, 2014 | 405 | 2014 |
Choline diet and its gut microbe–derived metabolite, trimethylamine N-oxide, exacerbate pressure overload–induced heart failure CL Organ, H Otsuka, S Bhushan, Z Wang, J Bradley, R Trivedi, ... Circulation: Heart Failure 9 (1), e002314, 2016 | 369 | 2016 |
Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis DJ Polhemus, K Kondo, S Bhushan, SC Bir, CG Kevil, T Murohara, ... Circulation: Heart Failure 6 (5), 1077-1086, 2013 | 193 | 2013 |
A novel hydrogen sulfide prodrug, SG 1002, promotes hydrogen sulfide and nitric oxide bioavailability in heart failure patients DJ Polhemus, Z Li, CB Pattillo, G Gojon Sr, G Gojon Jr, T Giordano, ... Cardiovascular therapeutics 33 (4), 216-226, 2015 | 170 | 2015 |
Evolution of hydrogen sulfide therapeutics to treat cardiovascular disease Z Li, DJ Polhemus, DJ Lefer Circulation Research 123 (5), 590-600, 2018 | 126 | 2018 |
The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure DJ Polhemus, JW Calvert, J Butler, DJ Lefer Scientifica 2014 (1), 768607, 2014 | 120 | 2014 |
Renal denervation prevents heart failure progression via inhibition of the renin-angiotensin system TE Sharp III, DJ Polhemus, Z Li, P Spaletra, JS Jenkins, JP Reilly, ... Journal of the American College of Cardiology 72 (21), 2609-2621, 2018 | 97 | 2018 |
Renal sympathetic denervation protects the failing heart via inhibition of neprilysin activity in the kidney DJ Polhemus, RK Trivedi, J Gao, Z Li, AL Scarborough, TT Goodchild, ... Journal of the American College of Cardiology 70 (17), 2139-2153, 2017 | 90 | 2017 |
Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure CL Organ, Z Li, TE Sharp III, DJ Polhemus, N Gupta, TT Goodchild, ... Journal of the American Heart Association 9 (10), e016223, 2020 | 82 | 2020 |
Zofenopril protects against myocardial ischemia–reperfusion injury by increasing nitric oxide and hydrogen sulfide bioavailability E Donnarumma, MJ Ali, AM Rushing, AL Scarborough, JM Bradley, ... Journal of the American Heart Association 5 (7), e003531, 2016 | 76 | 2016 |
Nitrite therapy improves left ventricular function during heart failure via restoration of nitric oxide–mediated cytoprotective signaling S Bhushan, K Kondo, DJ Polhemus, H Otsuka, CK Nicholson, YX Tao, ... Circulation research 114 (8), 1281-1291, 2014 | 75 | 2014 |
Combined angiotensin receptor–neprilysin inhibitors improve cardiac and vascular function via increased no bioavailability in heart failure RK Trivedi, DJ Polhemus, Z Li, D Yoo, H Koiwaya, A Scarborough, ... Journal of the American Heart Association 7 (5), e008268, 2018 | 61 | 2018 |
Hydrogen Sulfide Levels and Nuclear Factor‐Erythroid 2‐Related Factor 2 (NRF 2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI) KN Islam, DJ Polhemus, E Donnarumma, LP Brewster, DJ Lefer Journal of the American Heart Association 4 (5), e001986, 2015 | 61 | 2015 |
Radiofrequency renal denervation protects the ischemic heart via inhibition of GRK2 and increased nitric oxide signaling DJ Polhemus, J Gao, AL Scarborough, R Trivedi, KH McDonough, ... Circulation research 119 (3), 470-480, 2016 | 54 | 2016 |
Restoration of hydrogen sulfide production in diabetic mice improves reparative function of bone marrow cells Z Cheng, VNS Garikipati, E Nickoloff, C Wang, DJ Polhemus, J Zhou, ... Circulation 134 (19), 1467-1483, 2016 | 53 | 2016 |
Effects of storage‐aged red blood cell transfusions on endothelial function in hospitalized patients R Neuman, S Hayek, A Rahman, JC Poole, V Menon, S Sher, JL Newman, ... Transfusion 55 (4), 782-790, 2015 | 48 | 2015 |
Hydrogen sulfide attenuates renin angiotensin and aldosterone pathological signaling to preserve kidney function and improve exercise tolerance in heart failure Z Li, CL Organ, J Kang, DJ Polhemus, RK Trivedi, TE Sharp, JS Jenkins, ... JACC: Basic to Translational Science 3 (6), 796-809, 2018 | 41 | 2018 |
Effects of a novel hydrogen sulfide prodrug in a porcine model of acute limb ischemia AM Rushing, E Donnarumma, DJ Polhemus, KR Au, SE Victoria, ... Journal of vascular surgery 69 (6), 1924-1935, 2019 | 38 | 2019 |
Novel göttingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities TE Sharp III, AL Scarborough, Z Li, DJ Polhemus, HA Hidalgo, ... Basic to Translational Science 6 (2), 154-170, 2021 | 36 | 2021 |