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NJ Turner
NJ Turner
Professor of Chemical Biology, Manchester University
Verificeret mail på manchester.ac.uk
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Directed evolution drives the next generation of biocatalysts
NJ Turner
Nature chemical biology 5 (8), 567-573, 2009
9542009
Biocatalysis
EL Bell, W Finnigan, SP France, AP Green, MA Hayes, LJ Hepworth, ...
Nature Reviews Methods Primers 1 (1), 1-21, 2021
5022021
Biocatalytic approaches to the synthesis of enantiomerically pure chiral amines
D Ghislieri, NJ Turner
Topics in Catalysis 57, 284-300, 2014
4752014
Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities
MK Akhtar, NJ Turner, PR Jones
Proceedings of the National Academy of Sciences 110 (1), 87-92, 2013
4262013
Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades
FG Mutti, T Knaus, NS Scrutton, M Breuer, NJ Turner
Science 349 (6255), 1525-1529, 2015
4212015
Biocatalytic retrosynthesis
NJ Turner, E O'reilly
Nature chemical biology 9 (5), 285-288, 2013
4052013
Constructing biocatalytic cascades: in vitro and in vivo approaches to de novo multi-enzyme pathways
SP France, LJ Hepworth, NJ Turner, SL Flitsch
Acs Catalysis 7 (1), 710-724, 2017
3982017
Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products
D Ghislieri, AP Green, M Pontini, SC Willies, I Rowles, A Frank, G Grogan, ...
Journal of the American Chemical Society 135 (29), 10863-10869, 2013
3902013
Extending the application of biocatalysis to meet the challenges of drug development
PN Devine, RM Howard, R Kumar, MP Thompson, MD Truppo, NJ Turner
Nature Reviews Chemistry 2 (12), 409-421, 2018
3872018
Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes
V Köhler, YM Wilson, M Dürrenberger, D Ghislieri, E Churakova, T Quinto, ...
Nature Chemistry 5 (2), 93-99, 2013
3762013
A reductive aminase from Aspergillus oryzae
GA Aleku, SP France, H Man, J Mangas-Sanchez, SL Montgomery, ...
Nature chemistry 9 (10), 961-969, 2017
3602017
Discovery, engineering, and synthetic application of transaminase biocatalysts
I Slabu, JL Galman, RC Lloyd, NJ Turner
ACS Catalysis 7 (12), 8263-8284, 2017
3372017
Deracemization of α-methylbenzylamine using an enzyme obtained by in vitro evolution
M Alexeeva, A Enright, MJ Dawson, M Mahmoudian, NJ Turner
Angewandte Chemie-International Edition 41 (17), 3177-3180, 2002
318*2002
Cytochromes P450 as useful biocatalysts: addressing the limitations
E O'Reilly, V Köhler, SL Flitsch, NJ Turner
Chemical Communications 47 (9), 2490-2501, 2011
3102011
Enantioselective chemo‐and biocatalysis: partners in retrosynthesis
M Hönig, P Sondermann, NJ Turner, EM Carreira
Angewandte Chemie International Edition 56 (31), 8942-8973, 2017
2892017
Enantioselective oxidation of C–O and C–N bonds using oxidases
NJ Turner
Chemical reviews 111 (7), 4073-4087, 2011
2882011
A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines
CJ Dunsmore, R Carr, T Fleming, NJ Turner
Journal of the American Chemical Society 128 (7), 2224-2225, 2006
2722006
Directed evolution of enzymes for applied biocatalysis
NJ Turner
TRENDS in Biotechnology 21 (11), 474-478, 2003
2712003
Biocatalysis using immobilized enzymes in continuous flow for the synthesis of fine chemicals
MP Thompson, I Peñafiel, SC Cosgrove, NJ Turner
Organic process research & development 23 (1), 9-18, 2018
2672018
Enzyme catalysed deracemisation and dynamic kinetic resolution reactions
NJ Turner
Current opinion in chemical biology 8 (2), 114-119, 2004
2642004
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Artikler 1–20