| A living biobank of breast cancer organoids captures disease heterogeneity N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ... Cell 172 (1), 373-386. e10, 2018 | 1771 | 2018 |
| Designer matrices for intestinal stem cell and organoid culture N Gjorevski, N Sachs, A Manfrin, S Giger, ME Bragina, P Ordóñez-Morán, ... Nature 539 (7630), 560-564, 2016 | 1370 | 2016 |
| Sequential cancer mutations in cultured human intestinal stem cells J Drost, RH Van Jaarsveld, B Ponsioen, C Zimberlin, R Van Boxtel, ... Nature 521 (7550), 43-47, 2015 | 1158 | 2015 |
| Generation of tumor-reactive T cells by co-culture of peripheral blood lymphocytes and tumor organoids KK Dijkstra, CM Cattaneo, F Weeber, M Chalabi, J van de Haar, ... Cell 174 (6), 1586-1598. e12, 2018 | 965 | 2018 |
| Long‐term expanding human airway organoids for disease modeling N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ... The EMBO journal 38 (4), e100300, 2019 | 931 | 2019 |
| Identification of multipotent luminal progenitor cells in human prostate organoid cultures WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ... Cell 159 (1), 163-175, 2014 | 787 | 2014 |
| Organoid cultures for the analysis of cancer phenotypes N Sachs, H Clevers Current opinion in genetics & development 24, 68-73, 2014 | 404 | 2014 |
| Modelling Cryptosporidium infection in human small intestinal and lung organoids I Heo, D Dutta, DA Schaefer, N Iakobachvili, B Artegiani, N Sachs, ... Nature microbiology 3 (7), 814-823, 2018 | 378 | 2018 |
| Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon N Sasaki, N Sachs, K Wiebrands, SIJ Ellenbroek, A Fumagalli, ... Proceedings of the National Academy of Sciences 113 (37), E5399-E5407, 2016 | 369 | 2016 |
| Kidney failure in mice lacking the tetraspanin CD151 N Sachs, M Kreft, MA van den Bergh Weerman, AJ Beynon, TA Peters, ... Journal of Cell Biology 175 (1), 33-39, 2006 | 289 | 2006 |
| Differentiated human airway organoids to assess infectivity of emerging influenza virus J Zhou, C Li, N Sachs, MC Chiu, BHY Wong, H Chu, VKM Poon, D Wang, ... Proceedings of the National Academy of Sciences 115 (26), 6822-6827, 2018 | 282 | 2018 |
| Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages JM Rosenbluth, RCJ Schackmann, GK Gray, LM Selfors, CMC Li, ... Nature communications 11 (1), 1711, 2020 | 212 | 2020 |
| Integrin α3β1 inhibits directional migration and wound re-epithelialization in the skin C Margadant, K Raymond, M Kreft, N Sachs, H Janssen, A Sonnenberg Journal of Cell Science 122 (2), 278-288, 2009 | 183 | 2009 |
| Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids JF Dekkers, EJ van Vliet, N Sachs, JM Rosenbluth, O Kopper, HG Rebel, ... Nature protocols 16 (4), 1936-1965, 2021 | 173 | 2021 |
| Cell–matrix adhesion of podocytes in physiology and disease N Sachs, A Sonnenberg Nature Reviews Nephrology 9 (4), 200-210, 2013 | 170 | 2013 |
| Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome N Nicolaou, C Margadant, SH Kevelam, MR Lilien, MJS Oosterveld, ... The Journal of clinical investigation 122 (12), 4375-4387, 2012 | 153 | 2012 |
| BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance AA Duarte, E Gogola, N Sachs, M Barazas, S Annunziato, J R De Ruiter, ... Nature methods 15 (2), 134-140, 2018 | 143 | 2018 |
| Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels N Sachs, Y Tsukamoto, P Kujala, PJ Peters, H Clevers Development 144 (6), 1107-1112, 2017 | 143 | 2017 |
| MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells M Yañez-Mó, O Barreiro, P Gonzalo, A Batista, D Megías, L Genís, ... Blood, The Journal of the American Society of Hematology 112 (8), 3217-3226, 2008 | 138 | 2008 |
| Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures KPY Hui, RHH Ching, SKH Chan, JM Nicholls, N Sachs, H Clevers, ... The Lancet Respiratory Medicine 6 (11), 846-854, 2018 | 133 | 2018 |
Hans CleversHubrecht Institute - UtrechtCorreu electrònic verificat a hubrecht.eu