| Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets K Schulze, S Imbeaud, E Letouzé, LB Alexandrov, J Calderaro, ... Nature genetics 47 (5), 505-511, 2015 | 1734 | 2015 |
| Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling SM Wilhelm, L Adnane, P Newell, A Villanueva, JM Llovet, M Lynch Molecular cancer therapeutics 7 (10), 3129-3140, 2008 | 1697 | 2008 |
| Gene expression in fixed tissues and outcome in hepatocellular carcinoma Y Hoshida, A Villanueva, M Kobayashi, J Peix, DY Chiang, A Camargo, ... New England Journal of Medicine 359 (19), 1995-2004, 2008 | 1352 | 2008 |
| Genetic landscape and biomarkers of hepatocellular carcinoma J Zucman-Rossi, A Villanueva, JC Nault, JM Llovet Gastroenterology 149 (5), 1226-1239. e4, 2015 | 1318 | 2015 |
| Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma Y Hoshida, SMB Nijman, M Kobayashi, JA Chan, JP Brunet, DY Chiang, ... Cancer research 69 (18), 7385-7392, 2009 | 1239 | 2009 |
| Liver cancer cell of origin, molecular class, and effects on patient prognosis D Sia, A Villanueva, SL Friedman, JM Llovet Gastroenterology 152 (4), 745-761, 2017 | 1164 | 2017 |
| Pivotal role of mTOR signaling in hepatocellular carcinoma A Villanueva, DY Chiang, P Newell, J Peix, S Thung, C Alsinet, V Tovar, ... Gastroenterology 135 (6), 1972-1983. e11, 2008 | 843 | 2008 |
| Identification of an immune-specific class of hepatocellular carcinoma, based on molecular features D Sia, Y Jiao, I Martinez-Quetglas, O Kuchuk, C Villacorta-Martin, ... Gastroenterology 153 (3), 812-826, 2017 | 826 | 2017 |
| Focal gains of VEGFA and molecular classification of hepatocellular carcinoma DY Chiang, A Villanueva, Y Hoshida, J Peix, P Newell, B Minguez, ... Cancer research 68 (16), 6779-6788, 2008 | 776 | 2008 |
| Genomics and signaling pathways in hepatocellular carcinoma A Villanueva, P Newell, DY Chiang, SL Friedman, JM Llovet Seminars in liver disease 27 (01), 055-076, 2007 | 730 | 2007 |
| Advances in targeted therapies for hepatocellular carcinoma in the genomic era JM Llovet, A Villanueva, A Lachenmayer, RS Finn Nature reviews Clinical oncology 12 (7), 408-424, 2015 | 713 | 2015 |
| Tumour evolution in hepatocellular carcinoma AJ Craig, J Von Felden, T Garcia-Lezana, S Sarcognato, A Villanueva Nature reviews Gastroenterology & hepatology 17 (3), 139-152, 2020 | 689 | 2020 |
| β-catenin activation promotes immune escape and resistance to anti–PD-1 therapy in hepatocellular carcinoma M Ruiz de Galarreta, E Bresnahan, P Molina-Sánchez, KE Lindblad, ... Cancer discovery 9 (8), 1124-1141, 2019 | 676 | 2019 |
| Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes D Sia, Y Hoshida, A Villanueva, S Roayaie, J Ferrer, B Tabak, J Peix, ... Gastroenterology 144 (4), 829-840, 2013 | 596 | 2013 |
| Targeted therapies for hepatocellular carcinoma A Villanueva, JM Llovet Gastroenterology 140 (5), 1410-1426, 2011 | 524 | 2011 |
| A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis JM Llovet, Y Chen, E Wurmbach, S Roayaie, MI Fiel, M Schwartz, ... Gastroenterology 131 (6), 1758-1767, 2006 | 467 | 2006 |
| Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma A Villanueva, Y Hoshida, C Battiston, V Tovar, D Sia, C Alsinet, ... Gastroenterology 140 (5), 1501-1512. e2, 2011 | 466 | 2011 |
| Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression BK Yoo, L Emdad, Z Su, A Villanueva, DY Chiang, ND Mukhopadhyay, ... The Journal of clinical investigation 119 (3), 465-477, 2009 | 433 | 2009 |
| Systematic review: evidence‐based management of hepatocellular carcinoma–an updated analysis of randomized controlled trials PM Lopez, A Villanueva, JM Llovet Alimentary pharmacology & therapeutics 23 (11), 1535-1547, 2006 | 424 | 2006 |
| DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma A Villanueva, A Portela, S Sayols, C Battiston, Y Hoshida, ... Hepatology 61 (6), 1945-1956, 2015 | 411 | 2015 |