| Cassette dosing: rapid in vivo assessment of pharmacokinetics LW Frick, KK Adkison, KJ Wells-Knecht, P Woollard, DM Higton Pharmaceutical Science & Technology Today 1 (1), 12-18, 1998 | 96 | 1998 |
| Quantitative analysis of pharmaceuticals in biological fluids using high-performance liquid chromatography coupled to mass spectrometry: a review RS Plumb, GJ Dear, DN Mallett, DM Higton, S Pleasance, ... Xenobiotica 31 (8-9), 599-617, 2001 | 58 | 2001 |
| From definition to implementation: a cross-industry perspective of past, current and future MIST strategies ANR Nedderman, GJ Dear, S North, RS Obach, D Higton Xenobiotica 41 (8), 605-622, 2011 | 45 | 2011 |
| European Bioanalysis Forum recommendation: scientific validation of quantification by accelerator mass spectrometry D Higton, G Young, P Timmerman, R Abbott, M Knutsson, LD Svensson Bioanalysis 4 (22), 2669-2679, 2012 | 33 | 2012 |
| An investigation into the application of capillary electrochromatography-mass spectrometry (CEC-MS) for the analysis and quantification of a potential drug candidate in … CJ Paterson, RJ Boughtflower, D Higton, E Palmer Chromatographia 46 (11), 599-604, 1997 | 31 | 1997 |
| Determination of 4‐hydroxytamoxifen in mouse plasma in the pg/mL range by gradient capillary liquid chromatography/tandem mass spectrometry RS Plumb, H Warwick, D Higton, GJ Dear, DN Mallett Rapid Communications in Mass Spectrometry 15 (4), 297-303, 2001 | 28 | 2001 |
| AMS method validation for quantitation in pharmacokinetic studies with concomitant extravascular and intravenous administration G Lappin, M Seymour, G Young, D Higton, HM Hill Bioanalysis 3 (4), 393-405, 2011 | 27 | 2011 |
| Absorption and disposition of ranitidine hydrochloride in rat and dog PJ Eddershaw, AP Chadwick, DM Higton, SH Fenwick, P Linacre, ... Xenobiotica 26 (9), 947-956, 1996 | 23 | 1996 |
| Ask the experts: automation: part I. JL Allinson, KE Blick, L Cohen, D Higton, M Li Bioanalysis 5 (16), 1953-1962, 2013 | 22 | 2013 |
| The potential of serially coupled alkyl-bonded silica monolithic columns for high resolution separations of pharmaceutical compounds in biological fluids GJ Dear, DN Mallett, DM Higton, AD Roberts, SA Bird, H Young, ... Chromatographia 55 (3), 177-184, 2002 | 22 | 2002 |
| Use of cyclic ion mobility spectrometry (cIM)-mass spectrometry to study the intramolecular transacylation of diclofenac acyl glucuronide D Higton, ME Palmer, JPC Vissers, LG Mullin, RS Plumb, ID Wilson Analytical Chemistry 93 (20), 7413-7421, 2021 | 19 | 2021 |
| Cassette dosing: rapid estimation of in vivo pharmacokinetics LW Frick Med. Chem. Res. 8, 472-477, 1998 | 18 | 1998 |
| A rapid, automated approach to optimisation of multiple reaction monitoring conditions for quantitative bioanalytical mass spectrometry DM Higton Rapid Communications in Mass Spectrometry 15 (20), 1922-1930, 2001 | 17 | 2001 |
| An AMS method to determine analyte recovery from pharmacokinetic studies with concomitant extravascular and intravenous administration G Lappin, M Seymour, G Young, D Higton, HM Hill Bioanalysis 3 (4), 407-410, 2011 | 15 | 2011 |
| Investigation into Small Molecule Isomeric Glucuronide Metabolite Differentiation Using In Silico and Experimental Collision Cross-Section Values JRFB Connolly, J Munoz-Muriedas, C Lapthorn, D Higton, JPC Vissers, ... Journal of the American Society for Mass Spectrometry 32 (8), 1976-1986, 2021 | 12 | 2021 |
| Mass spectrometry: pharmaceutical sciences DM Higton, JM Oxford Applied Spectroscopy Reviews 30 (1-2), 81-118, 1995 | 7 | 1995 |
| Thermospray liquid chromatography-mass spectrometry for the characterization of sulphate ester conjugates GD Bowers, DM Higton, GR Manchee, J Oxford, DA Saynor Journal of Chromatography A 554 (1-2), 175-180, 1991 | 7 | 1991 |
| Conference Report: Drug Metabolism Discussion Group Short Meeting: Microsampling–The Next Big Thing K Jackson-Addie, K Woods, A Muir, C Smith, D Higton Bioanalysis 4 (23), 2775-2779, 2012 | 4 | 2012 |
| Fundamental aspects of mass spectrometry MV Doig, DM Higton Principles and practice of bioanalysis. 2nd ed. Boca Raton: Taulor & Francis …, 2008 | 4 | 2008 |
| Application of a tiered approach to the validation of accelerator MS assays D Higton, M Seymour Bioanalysis 6 (5), 665-672, 2014 | 2 | 2014 |
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