Foxp3 reprograms T cell metabolism to function in low-glucose, high-lactate environments A Angelin, L Gil-de-Gómez, S Dahiya, J Jiao, L Guo, MH Levine, Z Wang, ... Cell metabolism 25 (6), 1282-1293. e7, 2017 | 1070 | 2017 |
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer EB Eruslanov, PS Bhojnagarwala, JG Quatromoni, TL Stephen, ... The Journal of clinical investigation 124 (12), 5466-5480, 2014 | 691 | 2014 |
Helios expression is a marker of T cell activation and proliferation T Akimova, UH Beier, L Wang, MH Levine, WW Hancock PloS one 6 (8), e24226, 2011 | 506 | 2011 |
Substrate rigidity regulates human T cell activation and proliferation RS O’Connor, X Hao, K Shen, K Bashour, T Akimova, WW Hancock, ... The Journal of Immunology 189 (3), 1330-1339, 2012 | 337 | 2012 |
Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells EF de Zoeten, L Wang, K Butler, UH Beier, T Akimova, H Sai, JE Bradner, ... Molecular and cellular biology 31 (10), 2066-2078, 2011 | 292 | 2011 |
Essential role of mitochondrial energy metabolism in Foxp3+ T-regulatory cell function and allograft survival UH Beier, A Angelin, T Akimova, L Wang, Y Liu, H Xiao, MA Koike, ... The FASEB Journal 29 (6), 2315, 2015 | 286 | 2015 |
Lactate limits T cell proliferation via the NAD (H) redox state WJ Quinn, J Jiao, T TeSlaa, J Stadanlick, Z Wang, L Wang, T Akimova, ... Cell reports 33 (11), 2020 | 251 | 2020 |
Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity Y Liu, L Wang, J Predina, R Han, UH Beier, LCS Wang, V Kapoor, ... Nature medicine 19 (9), 1173-1177, 2013 | 243 | 2013 |
Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer S Singhal, J Stadanlick, MJ Annunziata, AS Rao, PS Bhojnagarwala, ... Science translational medicine 11 (479), eaat1500, 2019 | 242 | 2019 |
Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms UH Beier, L Wang, R Han, T Akimova, Y Liu, WW Hancock Science signaling 5 (229), ra45-ra45, 2012 | 225 | 2012 |
Second-generation histone deacetylase 6 inhibitors enhance the immunosuppressive effects of Foxp3+ T-regulatory cells JH Kalin, KV Butler, T Akimova, WW Hancock, AP Kozikowski Journal of Medicinal Chemistry 55 (2), 639-651, 2012 | 160 | 2012 |
Histone/protein deacetylases and T-cell immune responses T Akimova, UH Beier, Y Liu, L Wang, WW Hancock Blood, The Journal of the American Society of Hematology 119 (11), 2443-2451, 2012 | 155 | 2012 |
Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs T Akimova, G Ge, T Golovina, T Mikheeva, L Wang, JL Riley, ... Clinical Immunology 136 (3), 348-363, 2010 | 144 | 2010 |
Differing Effects of Rapamycin or Calcineurin Inhibitor on T‐Regulatory Cells in Pediatric Liver and Kidney Transplant Recipients T Akimova, BM Kamath, JW Goebel, KEC Meyers, EB Rand, A Hawkins, ... American Journal of Transplantation 12 (12), 3449-3461, 2012 | 134 | 2012 |
Ubiquitin-specific protease-7 inhibition impairs Tip60-dependent Foxp3+ T-regulatory cell function and promotes antitumor immunity L Wang, S Kumar, S Dahiya, F Wang, J Wu, K Newick, R Han, A Samanta, ... EBioMedicine 13, 99-112, 2016 | 133 | 2016 |
Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells UH Beier, T Akimova, Y Liu, L Wang, WW Hancock Current opinion in immunology 23 (5), 670-678, 2011 | 121 | 2011 |
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3 L Wang, Y Liu, R Han, UH Beier, TR Bhatti, T Akimova, MI Greene, ... The Journal of clinical investigation 125 (3), 1111-1123, 2015 | 117 | 2015 |
Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function Y Liu, L Wang, R Han, UH Beier, T Akimova, T Bhatti, H Xiao, PA Cole, ... Molecular and cellular biology 34 (21), 3993-4007, 2014 | 98 | 2014 |
Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity L Wang, Y Liu, UH Beier, R Han, TR Bhatti, T Akimova, WW Hancock Blood, The Journal of the American Society of Hematology 121 (18), 3631-3639, 2013 | 96 | 2013 |
HDAC inhibitor therapy in autoimmunity and transplantation WL Hancock WW, Akimova T, Beier UH, Liu Y Annals of the rheumatic diseases 71 (Suppl 2), i46-i54, 2012 | 91 | 2012 |