Targeting tumour proliferation with a small‐molecule inhibitor of AICAR transformylase homodimerization IB Spurr, CN Birts, F Cuda, SJ Benkovic, JP Blaydes, A Tavassoli Chembiochem 13 (11), 1628-1634, 2012 | 113 | 2012 |
Transcription of click‐linked DNA in human cells CN Birts, AP Sanzone, AH El‐Sagheer, JP Blaydes, T Brown, A Tavassoli Angewandte Chemie International Edition 53 (9), 2362-2365, 2014 | 103 | 2014 |
A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells CN Birts, SK Nijjar, CA Mardle, F Hoakwie, PJ Duriez, JP Blaydes, ... Chemical Science 4 (8), 3046-3057, 2013 | 96 | 2013 |
Catalytic and non-catalytic functions of human IIA phospholipase A2 CN Birts, CH Barton, DC Wilton Trends in Biochemical Sciences 35 (1), 28-35, 2010 | 79 | 2010 |
Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance CN Birts, R Harding, G Soosaipillai, T Halder, A Azim‐Araghi, M Darley, ... Biology of the Cell 103 (1), 1-19, 2011 | 78 | 2011 |
CtBPs promote cell survival through the maintenance of mitotic fidelity LM Bergman, CN Birts, M Darley, B Gabrielli, JP Blaydes Molecular and cellular biology 29 (16), 4539-4551, 2009 | 67 | 2009 |
p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators CN Birts, A Banerjee, M Darley, CR Dunlop, S Nelson, SK Nijjar, R Parker, ... Science signaling 13 (630), eaau9529, 2020 | 47 | 2020 |
A catalytically independent physiological function for human acute phase protein group IIA phospholipase A2: cellular uptake facilitates cell debris removal CN Birts, CH Barton, DC Wilton Journal of Biological Chemistry 283 (8), 5034-5045, 2008 | 40 | 2008 |
Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization A Banerjee, CN Birts, M Darley, R Parker, AH Mirnezami, J West, ... Carcinogenesis 40 (7), 871-882, 2019 | 33 | 2019 |
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 E Garcia, A Hayden, C Birts, E Britton, A Cowie, K Pickard, M Mellone, ... Scientific reports 6 (1), 32417, 2016 | 29 | 2016 |
CtBPs promote mitotic fidelity through their activities in the cell nucleus CN Birts, LM Bergman, JP Blaydes Oncogene 30 (11), 1272-1280, 2011 | 18 | 2011 |
Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2+ breast carcinoma CN Birts, C Savva, SA Laversin, A Lefas, J Krishnan, A Schapira, ... Scientific Reports 12 (1), 7802, 2022 | 12 | 2022 |
The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells A Banerjee, P Arvinrad, M Darley, SA Laversin, R Parker, MJJ Rose-Zerilli, ... Oncotarget 9 (33), 23274, 2018 | 11 | 2018 |
The role of three-dimensional in vitro models in modelling the inflammatory microenvironment associated with obesity in breast cancer RRR Blyth, CN Birts, SA Beers Breast Cancer Research 25 (1), 104, 2023 | 6 | 2023 |
Fcγ receptor–mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies A Rogel, FM Ibrahim, SM Thirdborough, F Renart-Depontieu, CN Birts, ... JCI insight 7 (19), e158444, 2022 | 6 | 2022 |
Age, obesity and hyperglycaemia: Activation of innate immunity initiates a series of molecular interactions involving anionic surfaces leading to COVID-19 morbidity and mortality CN Birts, DC Wilton Medical Hypotheses 155, 110646, 2021 | 6 | 2021 |
Glycolysis, via NADH‐dependent dimerisation of CtBPs, regulates hypoxia‐induced expression of CAIX and stem‐like breast cancer cell survival M Kreuzer, A Banerjee, CN Birts, M Darley, A Tavassoli, M Ivan, ... FEBS letters 594 (18), 2988-3001, 2020 | 5 | 2020 |
A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells. Chem Sci 2013; 4: 3046-57 CN Birts, SK Nijjar, CA Mardle, F Hoakwie, PJ Duriez, JP Blaydes, ... PUBMED, 0 | 3 | |
Could anionic LDL be a ligand for RAGE and TREM2 in addition to LOX-1 and thus exacerbate lung disease and dementia? CN Birts, DC Wilton Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1869 (8), 166837, 2023 | 2 | 2023 |
Clinical significance of crown-like structures to trastuzumab response in patients with primary invasive HER2+ breast cancer. C Savva, CN Birts, SA Laversin, A Lefas, J Krishnan, A Schapira, ... Journal of Clinical Oncology 39 (15_suppl), e12533-e12533, 2021 | 1 | 2021 |