Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration MH Hettiaratchi, L Krishnan, T Rouse, C Chou, TC McDevitt, RE Guldberg Science advances 6 (1), eaay1240, 2020 | 137 | 2020 |
Heparin microparticle effects on presentation and bioactivity of bone morphogenetic protein-2 MH Hettiaratchi, T Miller, JS Temenoff, RE Guldberg, TC McDevitt Biomaterials 35 (25), 7228-7238, 2014 | 117 | 2014 |
Human oligodendrogenic neural progenitor cells delivered with chondroitinase ABC facilitate functional repair of chronic spinal cord injury S Nori, M Khazaei, CS Ahuja, K Yokota, JE Ahlfors, Y Liu, J Wang, ... Stem Cell Reports 11 (6), 1433-1448, 2018 | 113 | 2018 |
Enhanced immunosuppression of T cells by sustained presentation of bioactive interferon-γ within three-dimensional mesenchymal stem cell constructs JA Zimmermann, MH Hettiaratchi, TC McDevitt Stem cells translational medicine 6 (1), 223-237, 2017 | 102 | 2017 |
A rapid method for determining protein diffusion through hydrogels for regenerative medicine applications MH Hettiaratchi, A Schudel, T Rouse, AJ García, SN Thomas, ... APL bioengineering 2 (2), 2018 | 73 | 2018 |
Effects of controlled dual growth factor delivery on bone regeneration following composite bone-muscle injury R Subbiah, A Cheng, MA Ruehle, MH Hettiaratchi, LE Bertassoni, ... Acta Biomaterialia 114, 63-75, 2020 | 66 | 2020 |
Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains MH Hettiaratchi, MJ O'Meara, CJ Teal, SL Payne, AJ Pickering, ... Journal of controlled release 297, 14-25, 2019 | 55 | 2019 |
Enhanced in vivo retention of low dose BMP-2 via heparin microparticle delivery does not accelerate bone healing in a critically sized femoral defect MH Hettiaratchi, T Rouse, C Chou, L Krishnan, HY Stevens, MTA Li, ... Acta biomaterialia 59, 21-32, 2017 | 50 | 2017 |
Inverse electron-demand diels–alder methylcellulose hydrogels enable the Co-delivery of chondroitinase ABC and neural progenitor cells V Delplace, AJ Pickering, MH Hettiaratchi, S Zhao, T Kivijärvi, ... Biomacromolecules 21 (6), 2421-2431, 2020 | 43 | 2020 |
Competitive protein binding influences heparin-based modulation of spatial growth factor delivery for bone regeneration MH Hettiaratchi, C Chou, N Servies, JM Smeekens, A Cheng, C Esancy, ... Tissue Engineering Part A 23 (13-14), 683-695, 2017 | 40 | 2017 |
Triple growth factor delivery promotes functional bone regeneration following composite musculoskeletal trauma R Subbiah, MA Ruehle, BS Klosterhoff, ASP Lin, MH Hettiaratchi, ... Acta Biomaterialia 127, 180-192, 2021 | 37 | 2021 |
Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability MH Hettiaratchi, MJ O’Meara, TR O’Meara, AJ Pickering, N Letko-Khait, ... Science Advances 6 (34), eabc6378, 2020 | 35 | 2020 |
Microparticle-mediated sequestration of cell-secreted proteins to modulate chondrocytic differentiation TE Rinker, BD Philbrick, MH Hettiaratchi, DM Smalley, TC McDevitt, ... Acta biomaterialia 68, 125-136, 2018 | 27 | 2018 |
Biomaterial strategies for controlling stem cell fate via morphogen sequestration MH Hettiaratchi, RE Guldberg, TC McDevitt Journal of Materials Chemistry B 4 (20), 3464-3481, 2016 | 26 | 2016 |
Modulated protein delivery to engineer tissue repair MH Hettiaratchi, MS Shoichet Tissue Engineering Part A 25 (13-14), 925-930, 2019 | 25 | 2019 |
Reactive sulfur and selenium species in the regulation of bone homeostasis AK Gilbert, TD Newton, MH Hettiaratchi, MD Pluth Free radical biology and medicine 190, 148-157, 2022 | 22 | 2022 |
Directed Evolution Enables Simultaneous Controlled Release of Multiple Therapeutic Proteins from Biopolymer‐Based Hydrogels CJ Teal, MH Hettiaratchi, MT Ho, A Ortin‐Martinez, AN Ganesh, ... Advanced Materials 34 (34), 2202612, 2022 | 20 | 2022 |
Biomaterials for protein delivery for complex tissue healing responses J Dorogin, JM Townsend, MH Hettiaratchi Biomaterials Science 9 (7), 2339-2361, 2021 | 16 | 2021 |
An Expanded Palette of Fluorescent COS/H2S‐Releasing Donors for H2S Delivery, Detection, and In Vivo Application KG Fosnacht, J Dorogin, PM Jefferis, MH Hettiaratchi, MD Pluth Angewandte Chemie International Edition 63 (24), e202402353, 2024 | 8 | 2024 |
Recent advances in regenerative medicine approaches for spinal cord injuries MH Hettiaratchi, T Führmann, MS Shoichet Current Opinion in Biomedical Engineering 4, 40-49, 2017 | 8 | 2017 |