| Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements AA Asuni, A Boutajangout, D Quartermain, EM Sigurdsson The Journal of Neuroscience 27 (34), 9115, 2007 | 641 | 2007 |
| GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila A Mudher, D Shepherd, TA Newman, P Mildren, JP Jukes, A Squire, ... Molecular psychiatry 9 (5), 522-530, 2004 | 334 | 2004 |
| Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons AR Saha, J Hill, MA Utton, AA Asuni, S Ackerley, AJ Grierson, CC Miller, ... Journal of Cell Science 117 (7), 1017-1024, 2004 | 224 | 2004 |
| An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-β derivatives EM Sigurdsson, E Knudsen, A Asuni, C Fitzer-Attas, D Sage, ... The Journal of neuroscience 24 (28), 6277, 2004 | 194 | 2004 |
| Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase A Mudher, S Chapman, J Richardson, A Asuni, G Gibb, C Pollard, ... The Journal of Neuroscience 21 (14), 4987-4995, 2001 | 163 | 2001 |
| Tau fragments for immunotherapy E Sigurdsson, A Asuni US Patent 8,012,936, 2011 | 114* | 2011 |
| Vaccination of Alzheimer's model mice with Aβ derivative in alum adjuvant reduces Aβ burden without microhemorrhages AA Asuni, A Boutajangout, H Scholtzova, E Knudsen, YS Li, ... European Journal of Neuroscience 24 (9), 2530-2542, 2006 | 101 | 2006 |
| Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration MA Kuszczyk, S Sanchez, J Pankiewicz, J Kim, M Duszczyk, M Guridi, ... The American journal of pathology 182 (5), 1750-1768, 2013 | 94 | 2013 |
| A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice EM Sigurdsson, YZ Wadghiri, L Mosconi, JA Blind, E Knudsen, A Asuni, ... Neurobiology of aging 29 (6), 836-847, 2008 | 91 | 2008 |
| GSK3α exhibits β‐catenin and tau directed kinase activities that are modulated by Wnt AA Asuni, C Hooper, CH Reynolds, S Lovestone, BH Anderton, R Killick European Journal of Neuroscience 24 (12), 3387-3392, 2006 | 91 | 2006 |
| Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease Z Sisková, DJ Mahad, C Pudney, G Campbell, M Cadogan, A Asuni, ... The American journal of pathology 177 (3), 1411, 2010 | 86 | 2010 |
| Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice JE Pankiewicz, M Guridi, J Kim, AA Asuni, S Sanchez, PM Sullivan, ... Acta neuropathologica communications 2, 1-11, 2014 | 76 | 2014 |
| The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons MA Utton, J Connell, AA Asuni, M van Slegtenhorst, M Hutton, R de Silva, ... The Journal of neuroscience 22 (15), 6394-6400, 2002 | 76 | 2002 |
| Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization S Quraishe, A Asuni, WC Boelens, V O'Connor, A Wyttenbach Neuroscience 153 (2), 483-491, 2008 | 75 | 2008 |
| Presenilin 1 independently regulates β-catenin stability and transcriptional activity R Killick, CC Pollard, AA Asuni, AK Mudher, JC Richardson, HT Rupniak, ... Journal of Biological Chemistry 276 (51), 48554-48561, 2001 | 63 | 2001 |
| Photoaffinity labeling of the benzodiazepine binding site of α1β3γ2 γ-aminobutyric acidA receptors with flunitrazepam identifies a subset of ligands that interact directly with … RM McKernan, S Farrar, I Collins, F Emms, A Asuni, K Quirk, H Broughton Molecular pharmacology 54 (1), 33-43, 1998 | 54* | 1998 |
| Highly specific and selective anti-pS396-tau antibody C10. 2 targets seeding-competent tau N Rosenqvist, AA Asuni, CR Andersson, S Christensen, JA Daechsel, ... Alzheimer's & Dementia: Translational Research & Clinical Interventions 4 …, 2018 | 51 | 2018 |
| Anti-Aβ antibody aducanumab regulates the proteome of senile plaques and closely surrounding tissue in a transgenic mouse model of Alzheimer’s disease J Bastrup, KH Hansen, TBG Poulsen, K Kastaniegaard, AA Asuni, ... Journal of Alzheimer's Disease 79 (1), 249-265, 2021 | 41 | 2021 |
| Efficient gene delivery to primary neuron cultures using a synthetic peptide vector system L Collins, AA Asuni, BH Anderton, JW Fabre Journal of neuroscience methods 125 (1-2), 113-120, 2003 | 39 | 2003 |
| Truncated apoE forms tangle-like structures in a neuronal cell line MC Ljungberg, R Dayanandan, A Asuni, TH Rupniak, BH Anderton, ... Neuroreport 13 (6), 867-870, 2002 | 38 | 2002 |
Einar M. SigurdssonProfessor of Neuroscience and Physiology and Psychiatryبريد إلكتروني تم التحقق منه على nyumc.org
