Wnt3a induces myofibroblast differentiation by upregulating TGF-β signaling through SMAD2 in a β-catenin-dependent manner JM Carthy, FS Garmaroudi, Z Luo, BM McManus PloS one 6 (5), e19809, 2011 | 197 | 2011 |
TGFβ signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders JM Carthy Journal of cellular physiology 233 (1), 98-106, 2018 | 173 | 2018 |
Versican: signaling to transcriptional control pathways M Rahmani, BW Wong, L Ang, CC Cheung, JM Carthy, H Walinski, ... Canadian journal of physiology and pharmacology 84 (1), 77-92, 2006 | 140 | 2006 |
Regulation of the versican promoter by the β-catenin-T-cell factor complex in vascular smooth muscle cells M Rahmani, JT Read, JM Carthy, PC McDonald, BW Wong, M Esfandiarei, ... Journal of Biological Chemistry 280 (13), 13019-13028, 2005 | 113 | 2005 |
Tamoxifen inhibits TGF‐β‐mediated activation of myofibroblasts by blocking non‐smad signaling through ERK1/2 JM Carthy, A Sundqvist, A Heldin, H Van Dam, D Kletsas, CH Heldin, ... Journal of cellular physiology 230 (12), 3084-3092, 2015 | 80 | 2015 |
1,25 Dihydroxyvitamin D3 Inhibits TGFβ1-Mediated Primary Human Cardiac Myofibroblast Activation A Meredith, S Boroomand, J Carthy, Z Luo, B McManus PloS one 10 (6), e0128655, 2015 | 59 | 2015 |
Collagen matrix remodeling in 3-dimensional cellular space resolved using second harmonic generation and multiphoton excitation fluorescence T Abraham, J Carthy, B McManus Journal of structural biology 169 (1), 36-44, 2010 | 44 | 2010 |
Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts JM Carthy, AJ Meredith, S Boroomand, T Abraham, Z Luo, D Knight, ... PLoS One 10 (7), e0133056, 2015 | 41 | 2015 |
In vitro and ex vivo vanadium antitumor activity in (TGF-β)-induced EMT. Synergistic activity with carboplatin and correlation with tumor metastasis in cancer patients S Petanidis, E Kioseoglou, K Domvri, P Zarogoulidis, JM Carthy, ... The International Journal of Biochemistry & Cell Biology 74, 121-134, 2016 | 38 | 2016 |
Analysis of Epithelial–Mesenchymal Transition Induced by Transforming Growth Factor β U Valcourt, J Carthy, Y Okita, L Alcaraz, M Kato, S Thuault, L Bartholin, ... TGF-β Signaling: Methods and Protocols, 147-181, 2016 | 30 | 2016 |
WNT3A induces a contractile and secretory phenotype in cultured vascular smooth muscle cells that is associated with increased gap junction communication JM Carthy, Z Luo, BM McManus Laboratory investigation 92 (2), 246-255, 2012 | 28 | 2012 |
A residue specific insight into the Arkadia E3 ubiquitin ligase activity and conformational plasticity M Birkou, CT Chasapis, KD Marousis, AK Loutsidou, D Bentrop, M Lelli, ... Journal of molecular biology 429 (15), 2373-2386, 2017 | 26 | 2017 |
Mapping of the Wnt/β-catenin/TCF response elements in the human versican promoter M Rahmani, JM Carthy, BM McManus Proteoglycans: Methods and Protocols, 35-52, 2012 | 25 | 2012 |
Versican localizes to the nucleus in proliferating mesenchymal cells JM Carthy, T Abraham, AJ Meredith, S Boroomand, BM McManus Cardiovascular Pathology 24 (6), 368-374, 2015 | 24 | 2015 |
Versican and CD44 in in vitro valvular interstitial cell injury and repair JM Carthy, S Boroomand, BM McManus Cardiovascular Pathology 21 (2), 74-82, 2012 | 21 | 2012 |
Minimally invasive imaging method based on second harmonic generation and multiphoton excitation fluorescence in translational respiratory research T Abraham, S Wadsworth, JM Carthy, DV Pechkovsky, B McMANUS Respirology 16 (1), 22-33, 2011 | 21 | 2011 |
Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation JM Carthy, M Stöter, C Bellomo, M Vanlandewijck, A Heldin, A Morén, ... Scientific Reports 6 (1), 29868, 2016 | 16 | 2016 |
Inhibition of vascular endothelial growth factor reduces cardiac allograft vasculopathy S Chatur, BWC Wong, JM Carthy, BM McManus The Journal of Heart and Lung Transplantation 35 (9), 1124-1130, 2016 | 14 | 2016 |
Commercially available preparations of recombinant Wnt3a contain non‐Wnt related activities which may activate TGF‐β signaling JM Carthy, U Engström, CH Heldin, A Moustakas Journal of cellular biochemistry 117 (4), 938-945, 2016 | 10 | 2016 |
Arkadia via SNON enables NODAL-SMAD2/3 signaling effectors to transcribe different genes depending on their levels JM Carthy, M Ioannou, V Episkopou bioRxiv, 487371, 2018 | 1 | 2018 |