| Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei MA Albert, JR Haanstra, V Hannaert, J Van Roy, FR Opperdoes, ... Journal of Biological Chemistry 280 (31), 28306-28315, 2005 | 211 | 2005 |
| Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia R Beekman, MG Valkhof, MA Sanders, PMH Van Strien, JR Haanstra, ... Blood, The Journal of the American Society of Hematology 119 (22), 5071-5077, 2012 | 196 | 2012 |
| Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes JR Haanstra, A van Tuijl, P Kessler, W Reijnders, PAM Michels, ... Proceedings of the National Academy of Sciences 105 (46), 17718-17723, 2008 | 191 | 2008 |
| Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites JR Haanstra, EB González-Marcano, M Gualdrón-López, PAM Michels Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (5), 1038-1048, 2016 | 147 | 2016 |
| Transcriptome‐wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co‐transcriptional degradation in determining mRNA levels A Fadda, M Ryten, D Droll, F Rojas, V Färber, JR Haanstra, C Merce, ... Molecular microbiology 94 (2), 307-326, 2014 | 126 | 2014 |
| EVI1 is critical for the pathogenesis of a subset of MLL-AF9–rearranged AMLs EMJ Bindels, M Havermans, S Lugthart, C Erpelinck, E Wocjtowicz, ... Blood, The Journal of the American Society of Hematology 119 (24), 5838-5849, 2012 | 102 | 2012 |
| Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei JR Haanstra, M Stewart, VD Luu, A van Tuijl, HV Westerhoff, C Clayton, ... Journal of Biological Chemistry 283 (5), 2495-2507, 2008 | 91 | 2008 |
| Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event MJH Kas, AW Bruijnzeel, JR Haanstra, VM Wiegant, RAH Adan Journal of molecular endocrinology 35 (1), 159-164, 2005 | 82 | 2005 |
| Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors A Wölfler, AA Danen-van Oorschot, JR Haanstra, M Valkhof, C Bodner, ... Blood, The Journal of the American Society of Hematology 116 (20), 4116-4125, 2010 | 74 | 2010 |
| Targeting pathogen metabolism without collateral damage to the host JR Haanstra, A Gerding, AM Dolga, FJ Sorgdrager, M Buist-Homan, ... Scientific Reports 7, 40406, 2017 | 68 | 2017 |
| Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism S Pieretti, JR Haanstra, M Mazet, R Perozzo, C Bergamini, F Prati, R Fato, ... PLoS Neglected Tropical Diseases 7 (1), e2012, 2013 | 66 | 2013 |
| Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis A Nilsson, JR Haanstra, M Engqvist, A Gerding, BM Bakker, U Klingmüller, ... Proceedings of the National Academy of Sciences 117 (19), 10294-10304, 2020 | 64 | 2020 |
| A domino effect in drug action: from metabolic assault towards parasite differentiation JR Haanstra, EJ Kerkhoven, A Van Tuijl, M Blits, M Wurst, R Van Nuland, ... Molecular microbiology 79 (1), 94-108, 2011 | 60 | 2011 |
| ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation MF Alemdehy, JR Haanstra, HWJ de Looper, PMH van Strien, ... Blood, The Journal of the American Society of Hematology 125 (25), 3937-3948, 2015 | 56 | 2015 |
| Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids B Szöör, JR Haanstra, M Gualdrón-López, PAM Michels Current Opinion in Microbiology 22, 79-87, 2014 | 55 | 2014 |
| Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux E Bosdriesz, MT Wortel, JR Haanstra, MJ Wagner, P De La Torre Cortes, ... Scientific reports 8 (1), 1-9, 2018 | 50 | 2018 |
| Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal … EB Antwi, JR Haanstra, G Ramasamy, B Jensen, D Droll, F Rojas, I Minia, ... BMC genomics 17, 1-16, 2016 | 50 | 2016 |
| Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes JR Haanstra, A van Tuijl, J van Dam, W van Winden, AGM Tielens, ... International journal for parasitology 42 (7), 667-673, 2012 | 43 | 2012 |
| Network-based selectivity of antiparasitic inhibitors BM Bakker, HE Assmus, F Bruggeman, JR Haanstra, E Klipp, ... Molecular biology reports 29 (1-2), 1-5, 2002 | 36 | 2002 |
| Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling AE Leroux, JR Haanstra, BM Bakker, RL Krauth-Siegel Journal of Biological Chemistry 288 (33), 23751-23764, 2013 | 35 | 2013 |
Barbara BakkerProfessor of Medical Systems Biology, University of Groningen, University Medical Centre Groningenبريد إلكتروني تم التحقق منه على umcg.nl