| Mutations in the gene for the granulocyte colony-stimulating–factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia F Dong, RK Brynes, N Tidow, K Welte, B Löwenberg, IP Touw New England Journal of Medicine 333 (8), 487-493, 1995 | 519 | 1995 |
| The Jak-Stat pathway in normal and perturbed hematopoiesis AC Ward, I Touw, A Yoshimura Blood, The Journal of the American Society of Hematology 95 (1), 19-29, 2000 | 431 | 2000 |
| Severe congenital neutropenias J Skokowa, DC Dale, IP Touw, C Zeidler, K Welte Nature Reviews Disease Primers 3 (1), 1-18, 2017 | 392 | 2017 |
| Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia NA Zambetti, Z Ping, S Chen, KJG Kenswil, MA Mylona, MA Sanders, ... Cell stem cell 19 (5), 613-627, 2016 | 383 | 2016 |
| Hematopoietic growth factors and their receptors in acute leukemia B Löwenberg, IP Touw Blood 81 (2), 281-292, 1993 | 304 | 1993 |
| Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation F Dong, C van Buitenen, K Pouwels, LH Hoefsloot, B Löwenberg, IP Touw Molecular and cellular biology 13 (12), 7774-7781, 1993 | 263 | 1993 |
| Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia B Lowenberg, W van Putten, IP Touw, R Delwel, V Santini New England Journal of Medicine 328 (9), 614-619, 1993 | 220 | 1993 |
| Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts R Horos, H IJspeert, D Pospisilova, R Sendtner, C Andrieu-Soler, ... Blood, The Journal of the American Society of Hematology 119 (1), 262-272, 2012 | 219 | 2012 |
| Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia. F Dong, LH Hoefsloot, AM Schelen, CA Broeders, Y Meijer, AJ Veerman, ... Proceedings of the National Academy of Sciences 91 (10), 4480-4484, 1994 | 215 | 1994 |
| G-CSF and its receptor in myeloid malignancy R Beekman, IP Touw Blood, The Journal of the American Society of Hematology 115 (25), 5131-5136, 2010 | 202 | 2010 |
| Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia R Beekman, MG Valkhof, MA Sanders, PMH Van Strien, JR Haanstra, ... Blood, The Journal of the American Society of Hematology 119 (22), 5071-5077, 2012 | 196 | 2012 |
| Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia I Touw, K Pouwels, T van Agthoven, R van Gurp, L Budel, ... | 193 | 1990 |
| Regulation of granulopoiesis by transcription factors and cytokine signals AC Ward, DM Loeb, AA Soede-Bobok, IP Touw, AD Friedman Leukemia 14 (6), 973-990, 2000 | 184 | 2000 |
| IFNγ induces monopoiesis and inhibits neutrophil development during inflammation AM de Bruin, SF Libregts, M Valkhof, L Boon, IP Touw, MA Nolte Blood, The Journal of the American Society of Hematology 119 (6), 1543-1554, 2012 | 180 | 2012 |
| G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth Q Zhu, L Xia, GB Mills, CA Lowell, IP Touw, SJ Corey Blood 107 (5), 1847-1856, 2006 | 180 | 2006 |
| Reduced hematopoietic reserves in DNA interstrand crosslink repair‐deficient Ercc1−/− mice JM Prasher, AS Lalai, C Heijmans‐Antonissen, RE Ploemacher, ... The EMBO journal 24 (4), 861-871, 2005 | 173 | 2005 |
| Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia F Dong, DC Dale, MA Bonilla, M Freedman, A Fasth, HJ Neijens, ... Leukemia 11 (1), 120-125, 1997 | 172 | 1997 |
| STAT3-mediated differentiation and survival of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27Kip1 JP de Koning, AA Soede-Bobok, AC Ward, AM Schelen, C Antonissen, ... Oncogene 19 (29), 3290-3298, 2000 | 171 | 2000 |
| Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia AC Ward, YM van Aesch, AM Schelen, IP Touw Blood, The Journal of the American Society of Hematology 93 (2), 447-458, 1999 | 166 | 1999 |
| Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders IP Touw, GJ van de Geijn Front Biosci 12 (1), 800-15, 2007 | 158 | 2007 |