Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 4170 | 2010 |
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus K Musunuru, A Strong, M Frank-Kamenetsky, NE Lee, T Ahfeldt, KV Sachs, ... Nature 466 (7307), 714-719, 2010 | 1295 | 2010 |
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ... PLoS genetics 8 (3), e1002607, 2012 | 580 | 2012 |
Engineered nucleic acids encoding a modified erythropoietin and their expression JP Schrum, NB Afeyan, GJ Sieczkiewicz, S Bancel, A De Fougerolles, ... US Patent 8,710,200, 2014 | 427 | 2014 |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project G Lettre, CD Palmer, T Young, KG Ejebe, H Allayee, EJ Benjamin, ... PLoS genetics 7 (2), e1001300, 2011 | 397 | 2011 |
Modified polynucleotides for the production of secreted proteins T Chakraborty, A De Fougerolles US Patent 9,192,651, 2015 | 319* | 2015 |
Modified polynucleotides for the production of biologics and proteins associated with human disease S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent 8,999,380, 2015 | 309 | 2015 |
Modified polynucleotides for the production of proteins associated with human disease S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent App. 13/791,910, 2014 | 260 | 2014 |
In vivo production of proteins S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent 9,221,891, 2015 | 247 | 2015 |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof JP Schrum, S Siddiqi, K Ejebe US Patent 9,334,328, 2016 | 240 | 2016 |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease Ibc 50k Cad Consortium PLoS genetics 7 (9), e1002260, 2011 | 228 | 2011 |
Engineered nucleic acids and methods of use thereof J Schrum, GJ Sieczkiewicz, K Ejebe, SM Elbashir US Patent App. 13/252,049, 2012 | 219 | 2012 |
DLIN-KC2-DMA lipid nanoparticle delivery of modified polynucleotides A De Fougerolles, KM Wood, SM Elbashir, JP Schrum US Patent 8,754,062, 2014 | 216 | 2014 |
Modified polynucleotides for the production of proteins S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent 9,254,311, 2016 | 185 | 2016 |
Modified polynucleotides A De Fougerolles, J Guild US Patent 10,501,512, 2019 | 168 | 2019 |
Candidate Gene Association Resource (CARe) design, methods, and proof of concept K Musunuru, G Lettre, T Young, DN Farlow, JP Pirruccello, KG Ejebe, ... Circulation: Cardiovascular Genetics 3 (3), 267-275, 2010 | 166 | 2010 |
Engineered nucleic acids and methods of use thereof JP Schrum, S Bancel, NB Afeyan US Patent 9,181,319, 2015 | 164 | 2015 |
Modified polynucleotides for the production of G-CSF A De Fougerolles, KM Wood, SM Elbashir, JP Schrum, K Ejebe US Patent 8,680,069, 2014 | 156 | 2014 |
Modified polynucleotides for treating protein deficiency S Bancel, T Chakraborty, A De Fougerolles, S Whoriskey US Patent App. 14/170,747, 2014 | 128 | 2014 |
Method of producing antibodies JP Schrum, K Ejebe, SM Elbashir US Patent App. 13/897,363, 2013 | 110 | 2013 |