Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells MA Antonyak, B Li, LK Boroughs, JL Johnson, JE Druso, KL Bryant, ... Proceedings of the National Academy of Sciences 108 (12), 4852-4857, 2011 | 584 | 2011 |
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ... nature 589 (7841), 270-275, 2021 | 531 | 2021 |
An atlas of substrate specificities for the human serine/threonine kinome JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ... Nature 613 (7945), 759-766, 2023 | 363 | 2023 |
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ... Science 366 (6466), 714-723, 2019 | 267 | 2019 |
Dietary fructose improves intestinal cell survival and nutrient absorption SR Taylor, S Ramsamooj, RJ Liang, A Katti, R Pozovskiy, N Vasan, ... Nature 597 (7875), 263-267, 2021 | 213 | 2021 |
Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops T Freisinger, B Klünder, J Johnson, N Müller, G Pichler, G Beck, ... Nature communications 4 (1), 1807, 2013 | 125 | 2013 |
New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes JL Johnson, JW Erickson, RA Cerione Journal of Biological Chemistry 284 (35), 23860-23871, 2009 | 125 | 2009 |
Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids Y Han, L Yang, X Duan, F Duan, BE Nilsson-Payant, TM Yaron, P Wang, ... BioRxiv, 2020.05. 05.079095, 2020 | 100 | 2020 |
Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy MR Lundquist, MD Goncalves, RM Loughran, E Possik, T Vijayaraghavan, ... Molecular cell 70 (3), 531-544. e9, 2018 | 96 | 2018 |
Interactions between epigenetics and metabolism in cancers J Yun, JL Johnson, CL Hanigan, JW Locasale Frontiers in oncology 2, 163, 2012 | 96 | 2012 |
Proteogenomic data and resources for pan-cancer analysis Y Li, Y Dou, FDV Leprevost, Y Geffen, AP Calinawan, F Aguet, Y Akiyama, ... Cancer cell 41 (8), 1397-1406, 2023 | 88 | 2023 |
A chemoproteomic strategy for direct and proteome-wide covalent inhibitor target-site identification CM Browne, B Jiang, SB Ficarro, ZM Doctor, JL Johnson, JD Card, ... Journal of the American Chemical Society 141 (1), 191-203, 2018 | 81 | 2018 |
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription JK Rimel, ZC Poss, B Erickson, ZL Maas, CC Ebmeier, JL Johnson, ... Genes & development 34 (21-22), 1452-1473, 2020 | 74 | 2020 |
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation Y Geffen, S Anand, Y Akiyama, TM Yaron, Y Song, JL Johnson, ... Cell 186 (18), 3945-3967. e26, 2023 | 71 | 2023 |
C-terminal di-arginine motif of Cdc42 protein is essential for binding to phosphatidylinositol 4, 5-bisphosphate-containing membranes and inducing cellular transformation JL Johnson, JW Erickson, RA Cerione Journal of Biological Chemistry 287 (8), 5764-5774, 2012 | 67 | 2012 |
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer A Jbara, KT Lin, C Stossel, Z Siegfried, H Shqerat, A Amar-Schwartz, ... Nature 617 (7959), 147-153, 2023 | 61 | 2023 |
Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry ER Kastenhuber, M Mercadante, B Nilsson-Payant, JL Johnson, ... Elife 11, e77444, 2022 | 61 | 2022 |
A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration LK Boroughs, MA Antonyak, JL Johnson, RA Cerione Journal of Biological Chemistry 286 (43), 37094-37107, 2011 | 60 | 2011 |
EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src MJ Begley, C Yun, CA Gewinner, JM Asara, JL Johnson, AJ Coyle, ... Nature structural & molecular biology 22 (12), 983-990, 2015 | 56 | 2015 |
Pan-cancer proteogenomics connects oncogenic drivers to functional states Y Li, E Porta-Pardo, C Tokheim, MH Bailey, TM Yaron, V Stathias, ... Cell 186 (18), 3921-3944. e25, 2023 | 52 | 2023 |