| The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 M Scheffner, BA Werness, JM Huibregtse, AJ Levine, PM Howley cell 63 (6), 1129-1136, 1990 | 5392 | 1990 |
| The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product N Dyson, PM Howley, K Münger, ED Harlow Science 243 (4893), 934-937, 1989 | 4082 | 1989 |
| Association of human papillomavirus types 16 and 18 E6 proteins with p53 BA Werness, AJ Levine, PM Howley Science 248 (4951), 76-79, 1990 | 3489 | 1990 |
| The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 M Scheffner, JM Huibregtse, RD Vierstra, PM Howley Cell 75 (3), 495-505, 1993 | 3210 | 1993 |
| The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes K Münger, WC Phelps, V Bubb, PM Howley, R Schlegel Journal of virology 63 (10), 4417-4421, 1989 | 1862 | 1989 |
| Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. K Münger, BA Werness, N Dyson, WC Phelps, E Harlow, PM Howley The EMBO journal 8 (13), 4099-4105, 1989 | 1572 | 1989 |
| A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. JM Huibregtse, M Scheffner, S Beaudenon, PM Howley Proceedings of the National Academy of Sciences 92 (7), 2563-2567, 1995 | 1509 | 1995 |
| A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. JM Huibregtse, M Scheffner, PM Howley The EMBO journal 10 (13), 4129-4135, 1991 | 1177 | 1991 |
| Human papillomavirus immortalization and transformation functions K Münger, PM Howley Virus research 89 (2), 213-228, 2002 | 1170 | 2002 |
| The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. M Scheffner, K Münger, JC Byrne, PM Howley Proceedings of the National Academy of Sciences 88 (13), 5523-5527, 1991 | 1104 | 1991 |
| Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines CC Baker, WC Phelps, V Lindgren, MJ Braun, MA Gonda, PM Howley Journal of virology 61 (4), 962-971, 1987 | 1016 | 1987 |
| Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo MG Wathelet, CH Lin, BS Parekh, LV Ronco, PM Howley, T Maniatis Molecular cell 1 (4), 507-518, 1998 | 955 | 1998 |
| The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A WC Phelps, CL Yee, K Münger, PM Howley Cell 53 (4), 539-547, 1988 | 890 | 1988 |
| In Vivo Ubiquitination and Proteasome-mediated Degradation of p53 CG Maki, JM Huibregtse, PM Howley Cancer research 56 (11), 2649-2654, 1996 | 880 | 1996 |
| Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the … S Chellappan, VB Kraus, B Kroger, K Munger, PM Howley, WC Phelps, ... Proceedings of the National Academy of Sciences 89 (10), 4549-4553, 1992 | 871 | 1992 |
| Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity LV Ronco, AY Karpova, M Vidal, PM Howley Genes & development 12 (13), 2061-2072, 1998 | 825 | 1998 |
| Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines C Yee, I Krishnan-Hewlett, CC Baker, R Schlegel, PM Howley The American journal of pathology 119 (3), 361, 1985 | 810 | 1985 |
| Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade L Huang, E Kinnucan, G Wang, S Beaudenon, PM Howley, JM Huibregtse, ... Science 286 (5443), 1321-1326, 1999 | 795 | 1999 |
| Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53 JM Huibregtse, M Scheffner, PM Howley Molecular and cellular biology 13 (2), 775-784, 1993 | 760 | 1993 |
| TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains JA Pietenpol, RW Stein, E Moran, P Yaciuk, R Schlegel, RM Lyons, ... Cell 61 (5), 777-785, 1990 | 756 | 1990 |
Karl MungerTufts University School of Medicineبريد إلكتروني تم التحقق منه على tufts.edu