Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation LA Mielke, SA Jones, M Raverdeau, R Higgs, A Stefanska, JR Groom, ... Journal of Experimental Medicine 210 (6), 1117-1124, 2013 | 342 | 2013 |
The H3K36me2 methyltransferase Nsd1 demarcates PRC2-mediated H3K27me2 and H3K27me3 domains in embryonic stem cells G Streubel, A Watson, SG Jammula, A Scelfo, DJ Fitzpatrick, G Oliviero, ... Molecular cell 70 (2), 371-379. e5, 2018 | 177 | 2018 |
A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018 | 155 | 2018 |
CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression CM Egan, U Nyman, J Skotte, G Streubel, S Turner, DJ O’Connell, ... Developmental cell 26 (3), 223-236, 2013 | 149 | 2013 |
The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation MA Kleinschmidt, G Streubel, B Samans, M Krause, UM Bauer Nucleic acids research 36 (10), 3202-3213, 2008 | 112 | 2008 |
Dynamic protein interactions of the polycomb repressive complex 2 during differentiation of pluripotent cells G Oliviero, GL Brien, A Waston, G Streubel, E Jerman, D Andrews, ... Molecular & Cellular Proteomics 15 (11), 3450-3460, 2016 | 81 | 2016 |
Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal G Streubel, DJ Fitzpatrick, G Oliviero, A Scelfo, B Moran, S Das, ... The EMBO journal 36 (15), 2216-2232, 2017 | 52 | 2017 |
The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis G Oliviero, N Munawar, A Watson, G Streubel, G Manning, V Bardwell, ... Scientific reports 5 (1), 18388, 2015 | 50 | 2015 |
PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines G Streubel, C Bouchard, H Berberich, MS Zeller, S Teichmann, ... PLoS Genetics 9 (3), e1003343, 2013 | 29 | 2013 |
Histone deacetylase inhibitor resminostat in combination with sorafenib counteracts platelet-mediated pro-tumoral effects in hepatocellular carcinoma G Streubel, S Schrepfer, H Kallus, U Parnitzke, T Wulff, F Hermann, ... Scientific Reports 11 (1), 9587, 2021 | 15 | 2021 |
Physiological evidence for a P2Y receptor responsive to diadenosine polyphosphates in human lung via Ca2+ release studies in bronchial epithelial cells W Laubinger, G Streubel, G Reiser Biochemical pharmacology 61 (5), 623-629, 2001 | 13 | 2001 |
MED 23: a new Mediator of H2B monoubiquitylation G Streubel, AP Bracken The EMBO journal 34 (23), 2863-2864, 2015 | 8 | 2015 |
Native gel analysis of macromolecular protein complexes in cultured mammalian cells N Munawar, G Olivero, E Jerman, B Doyle, G Streubel, K Wynne, ... Proteomics 15 (21), 3603-3612, 2015 | 7 | 2015 |
In human and rat lung membranes [35s] GTPγS binding is a tool for pharmacological characterization of G protein-coupled devucleotide receptors W Laubinger, T Weite, G Streubel, HJ Schäfer, G Reiser Life sciences 65 (14), PL183-PL190, 1999 | 6 | 1999 |
Mode-of-action of HDAC inhibitor resminostat in CTCL G Streubel, AC Bretz, T Wulff, U Parnitzke, H Kallus, K Kronthaler, ... European Journal of Cancer 156, S39-S40, 2021 | 1 | 2021 |
Multicenter, double-blind, randomized, placebo-controlled PhII-Study with Resminostat for the Maintenance Therapy of Patients with Mycosis fungoides in advanced Stage (Stage … R Stadler, J Scarisbrick, R Knobler, P Quaglino, P Reimann, M Borgmann, ... JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 18, 56-56, 2020 | | 2020 |
HDACi resminostat causes a sustained reduction of the pruritus mediator IL-31 in CTCL cells G Streubel, U Parnitzke, M Borgmann, S Hamm European Journal of Cancer 119, S38, 2019 | | 2019 |
Transcriptional impact of resminostat and other HDAC inhibitors on disease-related gene expression in CTCL AC Bretz, G Streubel, U Parnitzke, M Borgmann, S Hamm European Journal of Cancer 119, S10, 2019 | | 2019 |
Resminostat increases NK cell-mediated lysis of malignant cells beneficially affecting the function of opsonizing antibodies U Parnitzke, K Kronthaler, T Wulff, AC Bretz, G Streubel, M Borgmann, ... European Journal of Cancer 119, S3, 2019 | | 2019 |
PO-012 Pre-clinical insight into how platelet count affects the activity of HDACi resminostat in combination with the multi-kinase inhibitor sorafenib in HCC G Streubel, S Schrepfer, U Parnitzke, R Krauss, M Borgmann, S Hamm ESMO Open 3, A231-A232, 2018 | | 2018 |