A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018 | 155 | 2018 |
PRC2 functions in development and congenital disorders O Deevy, AP Bracken Development 146 (19), dev181354, 2019 | 124 | 2019 |
ATRX in-frame fusion neuroblastoma is sensitive to EZH2 inhibition via modulation of neuronal gene signatures ZA Qadeer, D Valle-Garcia, D Hasson, Z Sun, A Cook, C Nguyen, ... Cancer Cell 36 (5), 512-527. e9, 2019 | 75 | 2019 |
Simultaneous disruption of PRC2 and enhancer function underlies histone H3. 3-K27M oncogenic activity in human hindbrain neural stem cells GL Brien, RB Bressan, C Monger, D Gannon, E Lagan, AM Doherty, ... Nature Genetics 53 (8), 1221-1232, 2021 | 51 | 2021 |
Dominant negative and directional dysregulation of Polycomb function in EZH2-mutant human growth disorders O Deevy, C Monger, F Matrà, E Tuck, E Conway, S Rodighiero, Q Zhang, ... bioRxiv, 2023 | 3 | 2023 |
Dominant negative effects on H3K27 methylation by Weaver syndrome-associated EZH2 variants O Deevy, C Monger, F Matrà, E Tuck, E Conway, M Badonyi, D Nimmo, ... bioRxiv, 2023.06. 01.543208, 2023 | 1 | 2023 |
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells R McCole, J Nolan, DM Reck, C Monger, S Rustichelli, E Conway, ... Cell Reports 44 (1), 2025 | | 2025 |