Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease TTGHDLWG the Exome Sequencing Project New England Journal of Medicine, 2014 | 905* | 2014 |
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people MR Nelson, D Wegmann, MG Ehm, D Kessner, P St. Jean, C Verzilli, ... Science 337 (6090), 100-104, 2012 | 817 | 2012 |
Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease Myocardial Infarction Genetics Consortium Investigators New England Journal of Medicine 371 (22), 2072-2082, 2014 | 481 | 2014 |
A general framework for detecting disease associations with rare variants in sequencing studies DY Lin, ZZ Tang The American Journal of Human Genetics 89 (3), 354-367, 2011 | 339 | 2011 |
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ... The American Journal of Human Genetics 94 (2), 233-245, 2014 | 251* | 2014 |
Close social relationships correlate with human gut microbiota composition KA Dill-McFarland, ZZ Tang, JH Kemis, RL Kerby, G Chen, A Palloni, ... Scientific reports 9 (1), 703, 2019 | 250 | 2019 |
Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study EY Yang, L Chambless, AR Sharrett, SS Virani, X Liu, Z Tang, ... Stroke 43 (1), 103-108, 2012 | 167 | 2012 |
High dietary salt–induced DC activation underlies microbial dysbiosis-associated hypertension JF Ferguson, LA Aden, NR Barbaro, JP Van Beusecum, L Xiao, ... JCI insight 4 (13), e126241, 2019 | 166 | 2019 |
PERMANOVA-S: association test for microbial community composition that accommodates confounders and multiple distances ZZ Tang, G Chen, AV Alekseyenko Bioinformatics 32 (17), 2618-2625, 2016 | 159 | 2016 |
Multi-omic analysis of the microbiome and metabolome in healthy subjects reveals microbiome-dependent relationships between diet and metabolites ZZ Tang, G Chen, Q Hong, S Huang, HM Smith, RD Shah, M Scholz, ... Frontiers in Genetics 10, 454, 2019 | 143 | 2019 |
Integrated study of copy number states and genotype calls using high-density SNP arrays W Sun, FA Wright, Z Tang, SH Nordgard, PV Loo, T Yu, VN Kristensen, ... Nucleic acids research 37 (16), 5365-5377, 2009 | 136 | 2009 |
Gut microbiome variation modulates the effects of dietary fiber on host metabolism SM Murga-Garrido, Q Hong, TWL Cross, ER Hutchison, J Han, ... Microbiome 9 (1), 117, 2021 | 113 | 2021 |
Zero-inflated generalized Dirichlet multinomial regression model for microbiome compositional data analysis ZZ Tang, G Chen Biostatistics 20 (4), 698-713, 2019 | 93 | 2019 |
Quantitative trait analysis in sequencing studies under trait-dependent sampling DY Lin, D Zeng, ZZ Tang Proceedings of the National Academy of Sciences 110 (30), 12247-12252, 2013 | 77 | 2013 |
Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a US population: insights from the ARIC … EY Yang, V Nambi, Z Tang, SS Virani, E Boerwinkle, RC Hoogeveen, ... Journal of the American College of Cardiology 54 (25), 2388-2395, 2009 | 73 | 2009 |
Multi-trait analysis of rare-variant association summary statistics using MTAR L Luo, J Shen, H Zhang, A Chhibber, DV Mehrotra, ZZ Tang Nature Communications 11, 2020 | 54 | 2020 |
A general framework for association analysis of microbial communities on a taxonomic tree ZZ Tang, G Chen, AV Alekseyenko, H Li Bioinformatics 33 (9), 1278-1285, 2017 | 54 | 2017 |
MASS: meta-analysis of score statistics for sequencing studies ZZ Tang, DY Lin Bioinformatics 29 (14), 1803-1805, 2013 | 48 | 2013 |
Meta-analysis for discovering rare-variant associations: statistical methods and software programs ZZ Tang, DY Lin The American Journal of Human Genetics 97 (1), 35-53, 2015 | 43 | 2015 |
Exclusive breast-feeding, the early-life microbiome and immune response, and common childhood respiratory illnesses C Rosas-Salazar, MH Shilts, ZZ Tang, Q Hong, KN Turi, BM Snyder, ... Journal of Allergy and Clinical Immunology 150 (3), 612-621, 2022 | 42 | 2022 |