The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and … JM Hall, DP McDonnell Endocrinology 140 (12), 5566-5578, 1999 | 1456 | 1999 |
Cloning and expression of full-length cDNA encoding human vitamin D receptor. AR Baker, DP McDonnell, M Hughes, TM Crisp, DJ Mangelsdorf, ... Proceedings of the National Academy of Sciences 85 (10), 3294-3298, 1988 | 1304 | 1988 |
Human progesterone receptor A form is a cell-and promoter-specific repressor of human progesterone receptor B function. E Vegeto, MM Shahbaz, DX Wen, ME Goldman, BW O'Malley, ... Molecular endocrinology 7 (10), 1244-1255, 1993 | 1015 | 1993 |
Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay KW Gaido, LS Leonard, S Lovell, JC Gould, D Babaı̈, CJ Portier, ... Toxicology and applied pharmacology 143 (1), 205-212, 1997 | 908 | 1997 |
Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. MT Tzukerman, A Esty, D Santiso-Mere, P Danielian, MG Parker, RB Stein, ... Molecular endocrinology 8 (1), 21-30, 1994 | 904 | 1994 |
27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology ER Nelson, SE Wardell, JS Jasper, S Park, S Suchindran, MK Howe, ... Science 342 (6162), 1094-1098, 2013 | 884 | 2013 |
Connections and regulation of the human estrogen receptor DP McDonnell, JD Norris Science 296 (5573), 1642-1644, 2002 | 763 | 2002 |
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. DP McDonnell, DL Clemm, T Hermann, ME Goldman, JW Pike Molecular endocrinology 9 (6), 659-669, 1995 | 695 | 1995 |
Molecular cloning of complementary DNA encoding the avian receptor for vitamin D DP McDonnell, DJ Mangelsdorf, JW Pike, MR Haussler, BW O'Malley Science 235 (4793), 1214-1217, 1987 | 672 | 1987 |
Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol JC Gould, LS Leonard, SC Maness, BL Wagner, K Conner, T Zacharewski, ... Molecular and cellular endocrinology 142 (1-2), 203-214, 1998 | 636 | 1998 |
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells JP Chute, GG Muramoto, J Whitesides, M Colvin, R Safi, NJ Chao, ... Proceedings of the National Academy of Sciences 103 (31), 11707-11712, 2006 | 610 | 2006 |
The human estrogen receptor-α is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators AL Wijayaratne, DP McDonnell Journal of Biological Chemistry 276 (38), 35684-35692, 2001 | 553 | 2001 |
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β LA Paige, DJ Christensen, H Grøn, JD Norris, EB Gottlin, KM Padilla, ... Proceedings of the National Academy of Sciences 96 (7), 3999-4004, 1999 | 543 | 1999 |
Variant human breast tumor estrogen receptor with constitutive transcriptional activity SAW Fuqua, SD Fitzgerald, GC Chamness, AK Tandon, DP McDonnell, ... Cancer Research 51 (1), 105-109, 1991 | 531 | 1991 |
International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen … NZ Lu, SE Wardell, KL Burnstein, D Defranco, PJ Fuller, V Giguere, ... Pharmacological reviews 58 (4), 782-797, 2006 | 513 | 2006 |
Peptide antagonists of the human estrogen receptor JD Norris, LA Paige, DJ Christensen, CY Chang, MR Huacani, D Fan, ... Science 285 (5428), 744-746, 1999 | 487 | 1999 |
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor E Vegeto, GF Allan, WT Schrader, MJ Tsai, DP McDonnell, BW O'Malley Cell 69 (4), 703-713, 1992 | 478 | 1992 |
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors α and β C Chang, JD Norris, H Grøn, LA Paige, PT Hamilton, DJ Kenan, ... Molecular and cellular biology 19 (12), 8226-8239, 1999 | 467 | 1999 |
Evaluation of a recombinant yeast cell estrogen screening assay. NG Coldham, M Dave, S Sivapathasundaram, DP McDonnell, C Connor, ... Environmental health perspectives 105 (7), 734-742, 1997 | 462 | 1997 |
Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium T Improta-Brears, AR Whorton, F Codazzi, JD York, T Meyer, ... Proceedings of the National Academy of Sciences 96 (8), 4686-4691, 1999 | 461 | 1999 |