Dense genomic sampling identifies highways of pneumococcal recombination C Chewapreecha, SR Harris, NJ Croucher, C Turner, P Marttinen, ... Nature genetics 46 (3), 305-309, 2014 | 420 | 2014 |
SynergyFinder plus: toward better interpretation and annotation of drug combination screening datasets S Zheng, W Wang, J Aldahdooh, A Malyutina, T Shadbahr, Z Tanoli, ... Genomics, Proteomics and Bioinformatics 20 (3), 587-596, 2022 | 380 | 2022 |
mTORC1 regulates mitochondrial integrated stress response and mitochondrial myopathy progression NA Khan, J Nikkanen, S Yatsuga, C Jackson, L Wang, S Pradhan, ... Cell metabolism 26 (2), 419-428. e5, 2017 | 379 | 2017 |
Niacin cures systemic NAD+ deficiency and improves muscle performance in adult-onset mitochondrial myopathy E Pirinen, M Auranen, NA Khan, V Brilhante, N Urho, A Pessia, ... Cell metabolism 31 (6), 1078-1090. e5, 2020 | 274 | 2020 |
Host-microbe co-metabolism dictates cancer drug efficacy in C. elegans TA Scott, LM Quintaneiro, P Norvaisas, PP Lui, MP Wilson, KY Leung, ... Cell 169 (3), 442-456. e18, 2017 | 258 | 2017 |
Faecal and serum metabolomics in paediatric inflammatory bowel disease KL Kolho, A Pessia, T Jaakkola, WM de Vos, V Velagapudi Journal of Crohn's and Colitis 11 (3), 321-334, 2017 | 214 | 2017 |
DrugComb: an integrative cancer drug combination data portal B Zagidullin, J Aldahdooh, S Zheng, W Wang, Y Wang, J Saad, ... Nucleic acids research 47 (W1), W43-W51, 2019 | 212 | 2019 |
Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer A Malyutina, MM Majumder, W Wang, A Pessia, CA Heckman, J Tang PLoS computational biology 15 (5), e1006752, 2019 | 165 | 2019 |
Surveillance of European domestic pig populations identifies an emerging reservoir of potentially zoonotic swine influenza A viruses D Henritzi, PP Petric, NS Lewis, A Graaf, A Pessia, E Starick, A Breithaupt, ... Cell Host & Microbe 28 (4), 614-627. e6, 2020 | 111 | 2020 |
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs D Schatton, D Pla-Martin, MC Marx, H Hansen, A Mourier, I Nemazanyy, ... Journal of Cell Biology 216 (3), 675-693, 2017 | 90 | 2017 |
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data EF Douglass, RJ Allaway, B Szalai, W Wang, T Tian, A Fernández-Torras, ... Cell Reports Medicine 3 (1), 2022 | 49 | 2022 |
Integrated targeted metabolomic and lipidomic analysis: A novel approach to classifying early cystic precursors to invasive pancreatic cancer RA Gaiser, A Pessia, Z Ateeb, H Davanian, C Fernández Moro, ... Scientific reports 9 (1), 10208, 2019 | 34 | 2019 |
Validation and automation of a high-throughput multitargeted method for semiquantification of endogenous metabolites from different biological matrices using tandem mass … J Nandania, G Peddinti, A Pessia, M Kokkonen, V Velagapudi Metabolites 8 (3), 44, 2018 | 31 | 2018 |
Adipose tissue mitochondrial capacity associates with long-term weight loss success R Jokinen, R Rinnankoski-Tuikka, S Kaye, L Saarinen, S Heinonen, ... International journal of obesity 42 (4), 817-825, 2018 | 28 | 2018 |
Salmonella Typhimurium impairs glycolysis-mediated acidification of phagosomes to evade macrophage defense S Gutiérrez, J Fischer, R Ganesan, NJ Hos, G Cildir, M Wolke, A Pessia, ... PLoS pathogens 17 (9), e1009943, 2021 | 27 | 2021 |
Hydroxysteroid (17β) dehydrogenase 12 is essential for metabolic homeostasis in adult mice H Heikelä, ST Ruohonen, M Adam, R Viitanen, H Liljenbäck, O Eskola, ... American Journal of Physiology-Endocrinology and Metabolism 319 (3), E494-E508, 2020 | 26 | 2020 |
Combined gene essentiality scoring improves the prediction of cancer dependency maps W Wang, A Malyutina, A Pessia, J Saarela, CA Heckman, J Tang EBioMedicine 50, 67-80, 2019 | 24 | 2019 |
CD73 contributes to anti‐inflammatory properties of afferent lymphatic endothelial cells in humans and mice D Eichin, A Pessia, A Takeda, J Laakkonen, L Bellmann, M Kankainen, ... European journal of immunology 51 (1), 231-246, 2021 | 17 | 2021 |
drda: An R package for dose-response data analysis using logistic functions A Malyutina, J Tang, A Pessia Journal of Statistical Software 106, 1-26, 2023 | 15* | 2023 |
K-Pax2: Bayesian identification of cluster-defining amino acid positions in large sequence datasets A Pessia, Y Grad, S Cobey, JS Puranen, J Corander Microbial genomics 1 (1), e000025, 2015 | 15 | 2015 |